Peru Infectious Diseases Epidemiology Research Training*

描述（由申请人提供）：传染病继续对发展中国家构成重大挑战。在秘鲁，尽管在少数地区进行了集中的研究工作，但缺乏具有领导预防和控制工作所需专业知识的科学家。拟议中的项目将培养在秘鲁建立可持续研究基础设施所需的临界数量的科学家。我们提议对总共48名秘鲁调查人员进行培训，使其具备一名具有较强实验室诊断技能的流行病学家的核心能力，以便应对秘鲁面临的三大传染病挑战：疟疾、登革热和巴尔通体病。该计划将包括：热带医学文凭（JHU），公共卫生硕士（USUHS），博士（JHU）和博士后培训（NMRC）。此外，UPCH将开设一个新的流行病学硕士课程，以实现研究培训的自我可持续发展。学员将从没有其他培训补助金支持的地区选拔，优先考虑合格的卫生部候选人和大学附属候选人。培训方法遵循了我们的联盟之前在秘鲁应用的一种经过验证的创新模式，学员回报率高，“人才流失”最少。个性化的现场指导，成就驱动的逐步发展和学位授予培训将促进职业发展。课程将与实验室职员的实践培训和实地研究的参与相结合。根据个人需要，培训可侧重于实验室诊断研究、实地调查和/或病媒和水库研究。所有毕业生将准备一份研究方案，获得IRB的批准，进行独立研究，向同行评审的期刊提交手稿，并申请外部资金。

DESCRIPTION (provided by applicant): Infectious diseases continue to pose a significant challenge to developing countries. In Peru, despite concentrated research efforts in a few regions, there is a lack of scientists with the necessary expertise to lead prevention and control efforts. The proposed program will develop the critical mass of scientists needed to create a sustainable research infrastructure in Peru. We propose training a total of 48 Peruvian investigators in the core capacities of an epidemiologist with strong diagnostic laboratory skills in order to address three of Peru's main infectious diseases challenges: malaria, dengue and Bartonellosis. This program will include: Tropical Medicine Diplomas (JHU), Master's in Public Health (USUHS), PhDs (JHU) and post-doctoral training (NMRC). Additionally, a new Epidemiology Master's Program will be created at UPCH to allow self-sustainability of research training. Trainees will be selected from regions not supported by other training grants, favoring qualified Ministry of Health candidates and university-affiliated candidates. The training approach follows a proven, innovative model previously applied in Peru by our consortium with high rates of trainee return and minimal "brain drain". Individualized on-site mentorship, achievement-driven stepwise progression and degree-conferring training will foster career development. Coursework will be coupled with hands-on training during laboratory clerkships and participation in field research. Depending on individual needs, training may focus on lab-based diagnostic research, field investigations, and/or vector and reservoir studies. All graduates will prepare a research protocol, obtain IRB approval, conduct independent research, submit a manuscript to a peer-reviewed journal, and apply for external funding. This proposal is supported by a superb research and training environment. Our consortium has the most sophisticated laboratories and extensive field sites in Peru. It has secure, multi-year funding, the largest staff of US scientists permanently stationed in Peru, and direct access to world-class scientific infrastructure in the US. The NMRCD-UPCH-JHBSPH-USUHS consortium has a track record of 20+ years of collaborative research in Peru, sharing an extensive network of laboratories, field sites and clinical facilities, as well as substantial expertise in the diseases targeted by this application. Seven previous NIH training grants awarded to the consortium testify to its commitment to develop sustainable research in Peru.