Peru Infectious Diseases Epidemiology Research Training*

描述（由申请人提供）：传染病继续对发展中国家构成重大挑战。在秘鲁，尽管在少数几个区域集中开展了研究工作，但缺乏具有必要专门知识的科学家来领导预防和控制工作。拟议的计划将培养必要的科学家，以在秘鲁建立可持续的研究基础设施。我们提议对总共48名秘鲁调查人员进行培训，使其具备流行病学家的核心能力，具备强大的诊断实验室技能，以应对秘鲁面临的三大传染病挑战：疟疾、登革热和巴尔通体病。该计划将包括：热带医学文凭（JHU），公共卫生硕士（USUHS），博士（JHU）和博士后培训（NMRC）。此外，将在UPCH创建一个新的流行病学硕士课程，以实现研究培训的自我可持续性。受训人员将从没有得到其他培训赠款支助的区域挑选，优先考虑卫生部合格的候选人和大学附属候选人。培训方法采用了我们的联合体以前在秘鲁采用的一种行之有效的创新模式，受训人员回报率高，“人才流失”最少。个性化的现场指导，以成就为导向的逐步发展和学位授予培训将促进职业发展。课程将与实验室实习期间的实践培训和实地研究的参与相结合。根据个人需要，培训可侧重于实验室诊断研究、实地调查和/或媒介和储层研究。所有毕业生将准备一份研究方案，获得IRB批准，进行独立研究，向同行评审期刊提交手稿，并申请外部资金。 这一建议得到了一流的研究和培训环境的支持。我们的联合体在秘鲁拥有最先进的实验室和广泛的现场。它拥有可靠的多年资助，拥有最多的常驻秘鲁的美国科学家，并可直接使用美国世界级的科学基础设施。NMRCD-UPCH-JHBSPH-USUHS联合体在秘鲁有20多年的合作研究记录，共享广泛的实验室、实地和临床设施网络，以及在该应用所针对的疾病方面的大量专门知识。国家卫生研究院以前向该联合体提供的七笔培训赠款证明了它致力于在秘鲁发展可持续研究。

DESCRIPTION (provided by applicant): Infectious diseases continue to pose a significant challenge to developing countries. In Peru, despite concentrated research efforts in a few regions, there is a lack of scientists with the necessary expertise to lead prevention and control efforts. The proposed program will develop the critical mass of scientists needed to create a sustainable research infrastructure in Peru. We propose training a total of 48 Peruvian investigators in the core capacities of an epidemiologist with strong diagnostic laboratory skills in order to address three of Peru's main infectious diseases challenges: malaria, dengue and Bartonellosis. This program will include: Tropical Medicine Diplomas (JHU), Master's in Public Health (USUHS), PhDs (JHU) and post-doctoral training (NMRC). Additionally, a new Epidemiology Master's Program will be created at UPCH to allow self-sustainability of research training. Trainees will be selected from regions not supported by other training grants, favoring qualified Ministry of Health candidates and university-affiliated candidates. The training approach follows a proven, innovative model previously applied in Peru by our consortium with high rates of trainee return and minimal "brain drain". Individualized on-site mentorship, achievement-driven stepwise progression and degree-conferring training will foster career development. Coursework will be coupled with hands-on training during laboratory clerkships and participation in field research. Depending on individual needs, training may focus on lab-based diagnostic research, field investigations, and/or vector and reservoir studies. All graduates will prepare a research protocol, obtain IRB approval, conduct independent research, submit a manuscript to a peer-reviewed journal, and apply for external funding. This proposal is supported by a superb research and training environment. Our consortium has the most sophisticated laboratories and extensive field sites in Peru. It has secure, multi-year funding, the largest staff of US scientists permanently stationed in Peru, and direct access to world-class scientific infrastructure in the US. The NMRCD-UPCH-JHBSPH-USUHS consortium has a track record of 20+ years of collaborative research in Peru, sharing an extensive network of laboratories, field sites and clinical facilities, as well as substantial expertise in the diseases targeted by this application. Seven previous NIH training grants awarded to the consortium testify to its commitment to develop sustainable research in Peru.