CORE--ANIMAL

核心--动物

• 批准号: 6728400
• 负责人: KAREN A. FAGAN
• 金额: $ 8.09万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6728400
• 关键词: animal colony; biomedical facility; cow; hyperbaric chamber; laboratory mouse; laboratory rat; pulmonary circulation

DESCRIPTION (provided by applicant): Function: This core provides a range of services that are essential to the success of the overall program: * In vivo studies of pulmonary and systematic circulation. * Operation of hypo- and hyperbaric chambers. * Coordination of management of animals in large animal hypobaric chambers at Colorado State University in Fort Collins, CO. * Maintenance of breeding colonies for inbred mice. * Preparation and renewal of animal Services. Provided: In vivo studies of pulmonary and systematic circulation: The Animal Core provides a vital bridge linking in vitro studies in isolated organs and vessels and cultured cells to the in vivo setting. This permits the important test of relevance of concepts developed in reduced preparations to intact animals.

描述（由申请人提供）： 功能：该核心提供一系列服务，这些服务对整体的成功至关重要。 * 肺循环和体循环的体内研究。 * 操作低压舱和高压舱。 * 位于科罗拉多州柯林斯堡的科罗拉多州立大学大型动物低压舱中动物管理的协调。* 近交系小鼠繁殖群的维护。 * 动物服务的准备和更新。 提供：肺循环和体循环的体内研究：动物核心提供了连接 在离体器官和血管中的体外研究以及在体内环境中的培养细胞。这允许重要的测试的相关性的概念，在减少准备完整的动物。