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Activity-based probes as chemical tool to identify protease involved in mRNA splicing

Activity-based probes as chemical tool to identify protease involved in mRNA splicing
基于活性的探针作为化学工具来识别参与 mRNA 剪接的蛋白酶
批准号:
2599278
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2021
资助国家:
英国
项目状态:
未结题
起止时间:
2021 至 --

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中文摘要
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英文摘要
In this project, you will develop and apply chemical and biochemical tools to help to identify and characterize at the molecular level the protease(s) responsible for proteolytic processing of splicing components. This could reveal novel druggable targets and an alternative approach to modulate splicing indirectly, independent from targeting the RNA.
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