Analysis of CIGTS Visual Field Data

描述(由申请人提供)：CIGTS数据库和患者档案包含广泛的Humphrey 24-2视野(VF)信息收集，对607名新诊断的、以前未治疗的开角型青光眼(OAG)患者进行了9年的跟踪调查。这些患者被随机分为最初的内科治疗或外科治疗。该VF资源代表了关于VF变化的大量纵向跟踪数据。在访问以前输入的数据并输入来自所有收集的Humphrey 24-2视野的进一步数据后，将实现以下三个目标：1.确定眼压控制与最佳VF结果相关的方式。2.评估非裔美国人和白人渐进性室颤丧失的风险。3.确定眼压控制和种族以外的其他因素对进行性室颤丢失的相对影响。说明年龄、性别、家族史、合并症、吸烟、饮酒、屈光不正和基线室颤损害。

DESCRIPTION (provided by applicant): The CIGTS database and patient files contain an extensive collection of Humphrey 24-2 visual field (VF) information gathered over nine years of follow-up on 607 patients with newly-diagnosed, previously un-treated open-angle glaucoma (OAG). These patients were randomized to initial medical or surgical treatment. This VF resource represents a wealth of longitudinal follow-up data on VF change. The following three aims will be pursued after accessing previously entered data and entering further data from all collected Humphrey 24-2 visual fields: 1. Determine the ways in which intraocular pressure (IOP) control is associated with the best VF outcomes. 2. Evaluate the risk of progressive VF loss among African Americans and whites. 3. Determine the relative impact of factors other than IOP control and race on progressive VF loss. Address age, sex, family history, comorbidities, smoking, alcohol ingestion, refractive error, and baseline VF damage.