Spaced Retrieval/Cognitive Intervention/Brain Injury

描述（由申请人提供）：拟议的项目是一项为期两年的研究，在该研究中，患有慢性创伤性脑损伤（TBI）的成年人将通过电话进行训练，以使用无差错的训练程序-空间检索（SR）来改善日常记忆问题。记忆记忆包括在越来越长的时间间隔内成功记忆目标信息的练习。在佛罗里达州立大学进行的一项试点研究中，当治疗师通过电话实施SR治疗时，客户很容易掌握目标，并报告了对其他记忆相关问题的概括。拟议的研究旨在在一项具有更大样本的对照疗效研究中重复这些发现。两个研究地点，一个在佛罗里达州的塔拉哈西，另一个在俄亥俄州的克利夫兰，将分别招募20名慢性脑外伤患者参加一项通过电话进行的SR训练对日常记忆问题的影响的实验调查。治疗组将接受关于3个记忆相关目标的SR培训，对照组将接受注意力控制电话。本研究的具体目的是评估通过电话提供的SR在多大程度上(1)产生有效的目标掌握，(2)增强治疗目标的维持，以及(3)对其他相关的日常记忆问题产生普遍影响。参与者将在治疗开始前、治疗结束时和一个月后接受评估。治疗组和对照组将在日常记忆问题、记忆自我效能和生活质量方面进行比较。积极的研究结果将为临床医生提供一种新的策略，以解决当前记忆和认知康复技术对慢性TBI患者缺乏普遍影响的问题。本研究产生的数据将作为R01提交的基础。这一提议代表了Bourgeois博士在研究方向上的重大转变。到目前为止，她的职业生涯主要集中在痴呆症患者和他们的护理人员身上。尽管脑损伤和痴呆患者经历的记忆问题类型相似，但这两种疾病的神经损伤的病因和随后的恢复过程或退行性过程是完全不同的，因此不能保证干预策略从一个人群转移到另一个人群。这个探索性项目将提供一个机会，让我获得与患有TBI的客户以及一位在TBI方面知识渊博的合作研究者的第一手经验。

DESCRIPTION (provided by applicant): The proposed project is a two-year study in which adults with chronic traumatic brain injury (TBI) will be trained over the telephone to improve everyday memory problems using an errorless training procedure, Spaced-Retrieval (SR). SR involves practice at successfully remembering target information at increasingly longer time intervals. In a pilot study conducted at Florida State University, when therapists implemented SR therapy over the telephone, clients easily mastered targeted goals and reported generalization to other memory-related problems. The proposed study is designed to replicate these findings in a controlled efficacy study with a larger sample across settings. Two research sites, one in Tallahassee, Florida, and another in metropolitan Cleveland, Ohio, will each recruit 20 clients with chronic TBI to participate in an experimental investigation of the effects of SR training delivered over the phone on everyday memory problems. The treatment group will receive SR training on 3 memory-related goals and the control group will receive attention-control telephone calls. Specific aims of the study are to assess the extent to which SR delivered by phone (1) produces efficient goal mastery, (2) enhances maintenance of therapy goals, and (3) produces generalized effects on other related everyday memory problems. Participants will be assessed before therapy begins, at the end of therapy, and after one month. Treatment and control groups will be compared on measures of everyday memory problems, memory self-efficacy, and quality of life. Positive study outcomes will provide clinicians with a novel strategy for addressing the lack of generalized effects of current memory and cognitive rehabilitation techniques for persons with chronic TBI. The data generated from this study will serve as the basis of an R01 submission. This proposal represents a significant change in research direction for Dr. Bourgeois. Her career to date has focused on patients with dementia and their caregivers. Despite similarities in the types of memory problems experienced by persons with brain injuries and dementia, the etiology of the neurological damage and the subsequent course of recovery or degenerative process of the two disorders are sufficiently different that the transfer of intervention strategies from one population to the other is not guaranteed. This exploratory project will provide an opportunity to gain firsthand experience with clients with TBI and with a co-investigator knowledgeable in TBI.