Spaced Retrieval/Cognitive Intervention/Brain Injury

间隔检索/认知干预/脑损伤

• 批准号: 6851807
• 负责人: MICHELLE Suzanne BOURGEOIS
• 金额: $ 6.83万
• 依托单位: FLORIDA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-03-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6851807
• 关键词: brain injury; clinical research; cognition disorders; cognitive behavior therapy; goal oriented behavior; human subject; longitudinal human study; memory disorders; neural information processing; patient oriented research; quality of life; telemedicine; trauma

DESCRIPTION (provided by applicant): The proposed project is a two-year study in which adults with chronic traumatic brain injury (TBI) will be trained over the telephone to improve everyday memory problems using an errorless training procedure, Spaced-Retrieval (SR). SR involves practice at successfully remembering target information at increasingly longer time intervals. In a pilot study conducted at Florida State University, when therapists implemented SR therapy over the telephone, clients easily mastered targeted goals and reported generalization to other memory-related problems. The proposed study is designed to replicate these findings in a controlled efficacy study with a larger sample across settings. Two research sites, one in Tallahassee, Florida, and another in metropolitan Cleveland, Ohio, will each recruit 20 clients with chronic TBI to participate in an experimental investigation of the effects of SR training delivered over the phone on everyday memory problems. The treatment group will receive SR training on 3 memory-related goals and the control group will receive attention-control telephone calls. Specific aims of the study are to assess the extent to which SR delivered by phone (1) produces efficient goal mastery, (2) enhances maintenance of therapy goals, and (3) produces generalized effects on other related everyday memory problems. Participants will be assessed before therapy begins, at the end of therapy, and after one month. Treatment and control groups will be compared on measures of everyday memory problems, memory self-efficacy, and quality of life. Positive study outcomes will provide clinicians with a novel strategy for addressing the lack of generalized effects of current memory and cognitive rehabilitation techniques for persons with chronic TBI. The data generated from this study will serve as the basis of an R01 submission. This proposal represents a significant change in research direction for Dr. Bourgeois. Her career to date has focused on patients with dementia and their caregivers. Despite similarities in the types of memory problems experienced by persons with brain injuries and dementia, the etiology of the neurological damage and the subsequent course of recovery or degenerative process of the two disorders are sufficiently different that the transfer of intervention strategies from one population to the other is not guaranteed. This exploratory project will provide an opportunity to gain firsthand experience with clients with TBI and with a co-investigator knowledgeable in TBI.

描述(由申请者提供)：拟议的项目是一项为期两年的研究，将通过电话对患有慢性创伤性脑损伤(TBI)的成年人进行培训，以使用一种名为Spaced-Retrival(SR)的无错误培训程序来改善日常记忆问题。SR包括以越来越长的时间间隔成功地记住目标信息的练习。在佛罗里达州立大学进行的一项试点研究中，当治疗师通过电话实施SR治疗时，患者很容易掌握有针对性的目标，并报告对其他与记忆相关的问题的概括。这项拟议的研究旨在通过在不同环境中进行更大样本的受控疗效研究来重复这些发现。两个研究网站，一个在佛罗里达州的塔拉哈西，另一个在俄亥俄州的大都市克利夫兰，将分别招募20名患有慢性脑损伤的客户，参与一项关于通过电话提供的SR培训对日常记忆问题的影响的实验调查。治疗组将接受3个记忆相关目标的SR训练，而对照组将接受注意控制电话。这项研究的具体目的是评估通过电话传递的SR在多大程度上(1)产生有效的目标掌握，(2)增强治疗目标的维持，以及(3)对其他相关的日常记忆问题产生普遍影响。参与者将在治疗开始前、治疗结束时和一个月后接受评估。治疗组和对照组将在日常记忆问题、记忆自我效能和生活质量方面进行比较。积极的研究结果将为临床医生提供一种新的策略，以解决当前记忆和认知康复技术对慢性脑损伤患者缺乏普遍影响的问题。这项研究产生的数据将作为R01提交的基础。这一提议代表着布尔乔亚博士在研究方向上的重大变化。到目前为止，她的职业生涯一直专注于痴呆症患者和他们的照顾者。尽管脑损伤和痴呆症患者经历的记忆问题的类型相似，但神经损伤的病因以及随后两种疾病的康复或退化过程有很大的不同，因此不能保证干预策略从一个人群转移到另一个人群。这个探索性项目将提供一个机会，获得与TBI客户和具有TBI知识的合作调查员的第一手经验。