3D Printed Indicator Strips For Commercial Wound Dressings and Other Healthcare Products

用于商业伤口敷料和其他医疗保健产品的 3D 打印指示条

• 批准号: 2602596
• 金额: --
• 依托单位: Queen's University Belfast
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2602596
• 关键词: 3D; Printed; Indicator; Strips; Commercial

This project addresses the need for an inexpensive, disposable wound monitoring method that can be readily incorporated into current commercial wound dressings providing clinicians, nurses, and patients with a continuous stream of information about key biomarkers. This will help identify the condition/status of a wound and indicate those that are not healing properly and require further medical intervention. The proposed process involves 3D printing of a multi-analyte strip comprised of four different colour-based indicators which are selective in response to different volatile biomarkers. This strip will provide a semi-continuous, on-demand, stream of information concerning the composition of the headspace above the wound and contained by the dressing with regard to the different biomarkers. This strip will not be developed in isolation, but rather with an international producer of wound dressings, ConvaTec, who will help explore the capabilities and applicability of the 3DCIS (3D colorimetric indicator strip) indicator technology as it emerges from an associated EPSRC project to add value to their existing wound-care products. Collaboration with a company will allow for potential barriers to commercialisation of the sensor strip such as design & development, regulatory and clinical affairs, supply chain, manufacturing, and marketing to be addressed. The proposed project is in line with the recently announced 'Healthcare' research theme of the School of Chemistry and Chemical Engineering and QUB's PRP on Material and Advanced Technologies for Healthcare. The proposed project is also aligned with the EPSRC's extensive efforts in promoting impactful research for healthcare.

该项目解决了对一种廉价的一次性伤口监测方法的需求，该方法可以很容易地结合到当前的商业伤口敷料中，为临床医生、护士和患者提供有关关键生物标志物的连续信息流。这将有助于识别伤口的状况/状态，并指出那些没有正确愈合并需要进一步医疗干预的伤口。所提出的过程涉及多分析物条带的3D打印，该多分析物条带由四种不同的基于颜色的指示剂组成，这些指示剂对不同的挥发性生物标志物具有选择性。该条带将提供半连续、按需的信息流，涉及伤口上方顶部空间的组成以及敷料中包含的不同生物标志物的组成。该试纸不会单独开发，而是与伤口敷料的国际生产商ConvaTec合作，该公司将帮助探索3DCIS（3D比色指示试纸）指示技术的能力和适用性，因为它来自相关的EPSRC项目，以增加其现有伤口护理产品的价值。与一家公司的合作将允许解决传感器条商业化的潜在障碍，例如设计和开发，监管和临床事务，供应链，制造和营销。拟议的项目符合化学与化学工程学院最近宣布的“医疗保健”研究主题以及QUB关于医疗保健材料和先进技术的PRP。拟议的项目也与EPSRC在促进对医疗保健有影响力的研究方面的广泛努力保持一致。