High Resolution Electromechanical Mapping Of The Heart

我们继续开发硬件、MR脉冲序列和数据分析软件，以执行高分辨率的机械功能图，同时记录心脏周围电极“袜子”的电激活图。我们还开发了使用篮状电极同时进行心内标测和心外膜标测的硬件。电记录系统已被制成核磁共振兼容，因此核磁共振图像质量不会因心脏周围的袜子而降低。耦合机电激活图是通过将电图与MRI标记研究生成的机械图进行配准而生成的。缺血对机电组织的影响现在可以详细研究，也许可以精确区分有活力和无活力的组织。目前正在进行一系列的实验

We have continued to develop the hardware, MR pulse sequences and data analysis software to perform high resolution mechanical function maps while simultaneously recording electrical activation maps from an electrode "sock" surrounding the heart. We have also developed the hardware to perform endocardial mapping simultaneously with the epicardial mapping using a basket electrode. The electrical recording system has been made MR compatible so that the MR image quality is not degraded by the presence of the sock around the heart. Coupled electromechanical activation maps are being generated by registration of the electrical maps with the mechanical maps generated from MRI tagging studies. The effect of ischemia on the electromechanical can now be studied in detail, perhaps leading to the ability to precisely distinguish viable from non-viable tissue. A series of experiments is currently being done which maps both the electrical and mechanical behavoir of the heart DURING ventricular tachycardia.