Training Program in Translational Research in Imaging

描述(由申请人提供)：这项建议是在约翰霍普金斯大学建立影像翻译研究(TPTRI)的博士前培训计划。影像技术的创新改变了诊断和治疗医学。为了继续开发和应用这些技术，需要对基本的物理学和工程学有深刻的了解；此外，为了了解主要的临床需求，也需要对医学实践有同样深刻的理解。大多数情况下，这种背景和技能的结合是在一个团队中找到的，而不是一个人。在这个项目中，临床实习医生和博士后生物医学工程师将获得共同工作的经验，成为医学成像领域的创新者。该培训计划的目的是为生物医学工程专业的博士生创建导师团队，培养能够发明新技术并将这些技术转化为临床应用的成像科学家。该计划的导师结构将包括每个博士生的三名导师：一名工程导师(最有可能来自BME、EE、COMP Science、Radiology等)，一名临床医生导师，一名临床科学家，以及一名临床同行，他是以成像为核心资源的部门的住院医生或研究员。提供了一份全面的课程清单，并将为每个学生制作一份课程，以教授最先进的成像和信号处理技术。学员还将参加为放射学、心脏病学、肿瘤学等领域的新住院医生和研究员提供的入门讲座。学员还将从约翰霍普金斯大学临床和翻译研究所(ICTR)获得翻译研究技术和成本控制方面的培训。TPTRI项目将建立在约翰·霍普金斯大学现有的强大的成像研究社区和霍普金斯大学BME目前存在的一流博士项目的基础上。许多以前的BME学员在约翰霍普金斯大学攻读博士学位后，在工程学和临床研究人员的指导下，在医学成像科学领域找到了成功的职业生涯。这一新的TPTRI计划将在三个方面提供帮助：(1)激励现有的大型研究社区进入一个连贯的培训计划，(2)吸引顶尖学生进入成像科学，以及(3)引起工业合作伙伴对JHU进行的应用研究的关注。 公共卫生相关性(由申请者提供)：在越来越多的医学领域，成像正在成为一种必要的技术，并在其他昂贵的临床试验中成为关键的替代终点。对于成像科学家和工程师来说，理解临床需求的微妙之处，以及理解工程的独创性和创新如何将伟大的想法转化为实用技术，从来没有像现在这样重要。这项计划将有助于加快影像在诊断、治疗和疗效评估中的使用。

DESCRIPTION (provided by applicant): This proposal is to establish the pre-doctoral Training Program for Translational Research in Imaging (TPTRI) at Johns Hopkins University. Innovation in imaging technology has transformed diagnostic and therapeutic medicine. In order continue the development and application of these technologies, a firm understanding of the underlying physics and engineering is required; also, in order to understand the primary clinical needs, an equally deep understanding of the practice of medicine is required. Most often, this combination of backgrounds and skills are found in a team of people rather than a single person. In this program, both clinical residents and pre-doctoral biomedical engineers will gain experience working together to become innovators in medical imaging. The purpose of this training program is to create mentorship teams for PhD trainees in Biomedical Engineering that will produce imaging scientists who are able to invent new techniques and translate those techniques into clinical use. The mentorship structure of this program will include three mentors for each PhD candidate: an Engineering Mentor (most likely from BME, EE, Comp Science, Radiology etc.), a Clinician Mentor who is a clinician scientist, and a Clinical Peer who is a resident or fellow in a department in which imaging is a core resource. A comprehensive list of courses is available, and a curriculum for each student will be crafted to teach the most advanced imaging and signal processing techniques. Trainees will also attend the introductory lecture courses given to new residents and fellows in Radiology, Cardiology, Oncology etc. The trainees will also obtain training in translational research techniques and cost containment from the Institute for Clinical and Translational Research (ICTR) at Johns Hopkins. The TPTRI program will build on the strong imaging research community that exists at Johns Hopkins, and the superb PhD program that currently exists at Hopkins BME. Many previous BME trainees have found successful careers in medical imaging sciences after pursuing a PhD at Johns Hopkins involving mentorship from both engineering and clinical investigators. This new TPTRI program will help in three ways: (1) galvanize the existing large research community into a coherent training program, (2) attract the top students into the imaging sciences, and (3) bring the attention of industrial partners onto the applications research carried out at JHU. PUBLIC HEALTH RELEVANCE (provided by applicant): Imaging is becoming a necessary technique in an increasing number of fields within medicine, and a critical surrogate endpoint in otherwise prohibitively expensive clinical trials. It has never been more essential for imaging scientists and engineers to understand the subtleties of clinical needs; and to understand how engineering ingenuity and innovation can translate great ideas into practical techniques. This program will help accelerate the use of imaging in diagnosis treatment and therapy evaluation.