Training Program in Translational Research in Imaging

描述（由申请人提供）：本提案旨在建立约翰霍普金斯大学成像转化研究博士前培训计划（TPTRI）。影像技术的创新改变了诊断和治疗医学。为了继续发展和应用这些技术，需要对潜在的物理和工程有一个坚定的理解；此外，为了理解主要的临床需求，也需要对医学实践有同样深刻的理解。大多数情况下，这种背景和技能的结合是在一个团队中发现的，而不是在一个人身上。在这个项目中，临床住院医生和博士前生物医学工程师将获得共同工作的经验，成为医学成像的创新者。该培训计划的目的是为生物医学工程博士培训生创建指导团队，培养能够发明新技术并将这些技术转化为临床应用的成像科学家。该计划的指导结构将包括每位博士候选人的三位导师：一位工程导师（最有可能来自BME， EE, Comp Science， Radiology等），一位临床医生导师（临床医生科学家），以及一位临床同行（临床同行），他是住院医生或在以成像为核心资源的部门的研究员。一个全面的课程列表是可用的，每个学生的课程将精心制作，教最先进的成像和信号处理技术。受训者还将参加为新住院医师和放射学、心脏病学、肿瘤学等方面的研究员开设的介绍性讲座课程。受训者还将从约翰·霍普金斯大学临床和转化研究所获得转化研究技术和成本控制方面的培训。TPTRI项目将建立在约翰斯·霍普金斯大学强大的成像研究社区和霍普金斯大学BME现有的优秀博士项目的基础上。许多以前的BME学员在约翰霍普金斯大学攻读博士学位后，在工程和临床研究人员的指导下，在医学成像科学领域找到了成功的职业。这个新的TPTRI项目将在三个方面提供帮助：(1)激励现有的大型研究团体进行连贯的培训计划，(2)吸引顶尖学生进入成像科学领域，(3)引起工业合作伙伴对JHU进行的应用研究的关注。

DESCRIPTION (provided by applicant): This proposal is to establish the pre-doctoral Training Program for Translational Research in Imaging (TPTRI) at Johns Hopkins University. Innovation in imaging technology has transformed diagnostic and therapeutic medicine. In order continue the development and application of these technologies, a firm understanding of the underlying physics and engineering is required; also, in order to understand the primary clinical needs, an equally deep understanding of the practice of medicine is required. Most often, this combination of backgrounds and skills are found in a team of people rather than a single person. In this program, both clinical residents and pre-doctoral biomedical engineers will gain experience working together to become innovators in medical imaging. The purpose of this training program is to create mentorship teams for PhD trainees in Biomedical Engineering that will produce imaging scientists who are able to invent new techniques and translate those techniques into clinical use. The mentorship structure of this program will include three mentors for each PhD candidate: an Engineering Mentor (most likely from BME, EE, Comp Science, Radiology etc.), a Clinician Mentor who is a clinician scientist, and a Clinical Peer who is a resident or fellow in a department in which imaging is a core resource. A comprehensive list of courses is available, and a curriculum for each student will be crafted to teach the most advanced imaging and signal processing techniques. Trainees will also attend the introductory lecture courses given to new residents and fellows in Radiology, Cardiology, Oncology etc. The trainees will also obtain training in translational research techniques and cost containment from the Institute for Clinical and Translational Research (ICTR) at Johns Hopkins. The TPTRI program will build on the strong imaging research community that exists at Johns Hopkins, and the superb PhD program that currently exists at Hopkins BME. Many previous BME trainees have found successful careers in medical imaging sciences after pursuing a PhD at Johns Hopkins involving mentorship from both engineering and clinical investigators. This new TPTRI program will help in three ways: (1) galvanize the existing large research community into a coherent training program, (2) attract the top students into the imaging sciences, and (3) bring the attention of industrial partners onto the applications research carried out at JHU. PUBLIC HEALTH RELEVANCE (provided by applicant): Imaging is becoming a necessary technique in an increasing number of fields within medicine, and a critical surrogate endpoint in otherwise prohibitively expensive clinical trials. It has never been more essential for imaging scientists and engineers to understand the subtleties of clinical needs; and to understand how engineering ingenuity and innovation can translate great ideas into practical techniques. This program will help accelerate the use of imaging in diagnosis treatment and therapy evaluation.