Neural circuits underlying trauma memory in patients with co-morbid PTSD and psychosis prior to psychological therapy

心理治疗前共病 PTSD 和精神病患者的创伤记忆背后的神经回路

• 批准号: 2605264
• 金额: --
• 依托单位: King's College London
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2605264
• 关键词: Neural; circuits; underlying; trauma; memory

ecological momentary assessment. the neurobiological basis of this therapy, and therapies like it which address the restructuring of trauma memory recall, is poorly understood. The link between psychosis and PTSD experiences is also well documented but its neural basis is poorly understood. Symptoms of both SSD and PTSD are linked to these trauma memory representations, but there is a paucity of literature on the dual-diagnosed PTSD-SSD population, particularly around the neural basis of these experiences. The proposed project will use functional MRI (fMRI), behavioural measures, and experience sampling method (ESM) to investigate the neural representations of trauma memory recall and the symptom correlates.

生态瞬时评估。这种疗法的神经生物学基础，以及类似的解决创伤记忆回忆重建的疗法，还知之甚少。精神病和PTSD经历之间的联系也有很好的记录，但其神经基础却知之甚少。SSD和PTSD的症状都与这些创伤记忆表征有关，但关于双重诊断的PTSD-SSD人群的文献很少，特别是围绕这些经历的神经基础。该项目将使用功能性磁共振成像（fMRI），行为测量和经验抽样方法（ESM）来研究创伤记忆回忆的神经表征和症状相关性。