Towards the Rational Design and Scale-up of Green Photoreactors

化学反应的光化学激活为热激活过程提供了互补的合成途径，这可以更节能、更可持续。此外，它们可以更节省原子，减少所需的合成步骤数量(步骤经济)，在许多情况下，c提供了比热激活过程更好的选择性。然而，尽管光化学的研究已有150多年的历史，但很少有人将光化学过程用于工业规模。这项研究项目将通过阐明面向目标的光反应堆设计的基本概念来解决克服这一障碍的关键挑战。为此，我们将使用关于空间分辨光子强度的光反应堆的尖端建模，以及使用包括停流和周期操作在内的高级表征方法的实验验证，并结合实验设计和自动化测试。在建模能力和发展的理解基础上，该项目将致力于使用可扩展反应堆概念的合理设计来建造、测试和对照商业可获得的反应堆解决方案进行基准测试。

Photochemical activation of chemical reactions promises complementary synthetic pathways to thermally activated processes, which can be much more energy-efficient, and sustainable. Moreover, they can be more atom economic and reduce the required number of synthetic steps (step economy) and in many cases c offers superior selectivity over thermally activated processes. Nevertheless, and despite the fact that there has been research on photochemistry for more than 150 years, few photochemical processes are used on an industrial scale. This research project will tackle the key challenges to overcoming this barrier by elucidating the fundamental concepts for target-oriented photoreactor design. To this end we will use cutting-edge modelling of photoreactors with respect to spatially resolved photon intensity, as well as experimental validation using advanced methods of characterization including stopped flow and periodic operation coupled with design of experiments and automated testing. Building on the modelling capabilities and the developed understanding, the project will aim to use the rational design of a scalable reactor concept to construct, test and benchmark against commercially available reactor solutions.