Guiding Adaptive Behaviour by Memory of Different Timescales and the Underlying Neural Mechanisms

我们的大脑在将传入的感官信号与过去的经验相匹配方面表现出色，这引导了选择性注意力，并使我们能够根据预测和期望进行适应性和动态的行为。不同时间尺度的记忆参与了知觉和表现的引导，但到目前为止，我们仍然缺乏对远程长期记忆（LTM）和当前工作记忆（WM）如何共同作用以“预成员”经验的清晰理解，我们也不知道潜在的神经机制。该项目将设计新颖的行为任务，结合神经成像技术（如功能磁共振成像，脑磁图/脑电图）和计算建模，以阐明记忆的前瞻性如何以多时间尺度和互动的方式运作。

Our brain is extraordinary at matching incoming sensory signals to past experiences, which guides selective attention and allows us to behave adaptively and dynamically based on predictions and expectations. Memories of different timescales are involved in guiding perception and performance, but so far we still lack a clear understanding of how remote long-term memories (LTM) and current working memories (WM) work together to "premember" experience, and neither do we know the underlying neural mechanisms. This project will design novel behavioural tasks, in combination with neuroimaging techniques (e.g. fMRI, MEG/EEG) and computational modelling, to elucidate how the prospective nature of memory operates in a multi-timescale and interactive way.