Total Synthesis of Complex Marine Natural Products by Ring Expansion

该项目将涉及开发新的、高效和通用的方法，以全面合成结构复杂的海洋天然产品，这些产品包含多个融合环、立体中心和敏感功能。涉及环扩张反应的合成方法将应用于快速、简洁、高效地合成具有结构挑战性和生物活性的海洋天然产物的核心结构。

The project will involve the development of new, highly efficient, and general methods for the total synthesis of structirally complex natural producrs of marine origin that contain multiple fused rings, stereogenic centres and sensitive functionality. Synthetic methods involving ring expansion reactions will be applied to the rapid, concise and efficient syntheses of the core structures of structurally challenging and biologically active marine natural products.