Total Synthesis of Complex Marine Natural Products by Ring Expansion

扩环法全合成复杂海洋天然产物

• 批准号: 2607116
• 金额: --
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2607116
• 关键词: Total; Synthesis; Complex; Marine; Natural

The project will involve the development of new, highly efficient, and general methods for the total synthesis of structirally complex natural producrs of marine origin that contain multiple fused rings, stereogenic centres and sensitive functionality. Synthetic methods involving ring expansion reactions will be applied to the rapid, concise and efficient syntheses of the core structures of structurally challenging and biologically active marine natural products.

该项目将涉及开发新的、高效的和通用的方法，用于全合成含有多个稠环、立体中心和敏感功能的结构复杂的海洋来源天然产物。涉及扩环反应的合成方法将被应用于结构上具有挑战性和生物活性的海洋天然产物的核心结构的快速，简洁和有效的合成。