Postrhinal cortex and attentional functions

鼻后皮层和注意力功能

• 批准号: 6936773
• 负责人: KARA L AGSTER
• 金额: $ 2.72万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-01 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6936773
• 关键词: afferent nerve; attention; behavior test; behavioral /social science research tag; cognition; electrophysiology; hippocampus; laboratory rat; neural information processing; neuroregulation; parietal lobe /cortex; predoctoral investigator; synapses

DESCRIPTION (provided by applicant): The link between memory and attention has long been recognized; however, the precise signal that serves to select stimuli for further mnemonic processing has yet to be identified. Since attention can be rapidly oriented from one stimulus to another, the signal that initiates subsequent mnemonic processing must be closely tied to the events within conscious attention at all times to ensure that storage is properly aligned with content (Posner, 1984). Postrhinal cortex, the rodent homologue of the primate parahippocampal cortex, has diffuse anatomical connections with neural regions associated with memory and attention systems (Burwell and Amaral, 1998b). This places postrhinal cortex in an ideal position to interface these two systems. Additionally, current behavioral and electrophysiological data suggest that postrhinal cortex has a role in the orienting of attention (Bucci and Burwell, in press; Burwell and Hafeman, 2003). The goal of the proposed study is to delineate the afferent connectivity of postrhinal cortex and characterize the behavioral significance of this region's role in cognitive processing using single unit recording techniques in behaving rats.

描述（由申请人提供）：长期以来已经认识到记忆与注意力之间的联系；但是，尚未确定为进一步的助记符处理选择刺激的确切信号。由于可以从一种刺激到另一种刺激迅速将注意力定向，因此启动随后的助记符处理的信号必须始终与有意识注意的事件紧密相关，以确保存储与内容正确对齐（Posner，1984）。 Pertrhinal皮层是灵长类动物偏头皮皮层的啮齿动物同源物，它与与记忆和注意力系统相关的神经区域扩散了解剖学连接（Burwell and Amaral，1998b）。这使后皮层处于接口这两个系统的理想位置。此外，当前的行为和电生理数据表明，后皮层在注意力方向上起作用（Bucci和Burwell，印刷中； Burwell and Hafeman，2003年）。拟议的研究的目的是描述后皮层的传入连通性，并表征该地区在行为大鼠中使用单个单位记录技术在认知处理中的作用的行为意义。