CORE--PATIENT ACCESS

描述(由申请人提供)：此关键任务核心将促进快速 对急性中风患者的介绍、评估和治疗，确保项目1-3中的临床研究迅速招募患者，并确保至少12名患者将在2小时内接受静脉注射TPA治疗。在每个颁奖年的开始。患者访问核心的使命将通过四个具体目标来实现。目标1是在加州大学洛杉矶分校医学中心、加州大学洛杉矶分校中风网络医院和整个洛杉矶市的集水区教育有风险的个人，了解中风的警告迹象、出现症状时应采取的步骤以及脑部疾病早期治疗的重要性。这一目标将通过在加州大学洛杉矶分校医学中心和加州大学洛杉矶分校中风网络医院集散区和整个洛杉矶通过讲座、外展计划、健康博览会和额外的教育计划来实现。目标2是在加州大学洛杉矶分校医学中心中风网络医院的集水区和整个洛杉矶市教育院前护理人员关于中风识别、院前中风治疗、接收医院的现场预先通知以及快速交通的重要性。这一目标将通过在全市范围内教育护理人员使用洛杉矶院前卒中筛查(LAPSS)和洛杉矶运动量表(LAMS)，以及通过设计、验证和传播LAPSS的调度员版本来实现。目标3是优化加州大学洛杉矶分校医学中心、加州大学洛杉矶分校卒中网络医院和整个洛杉矶市的急诊科和急性中风患者的院内管理。这一目标将通过扩大快速反应急性卒中团队活动来实现 加州大学洛杉矶分校医学中心和加州大学洛杉矶分校中风网络医院。目标4是确保参与加州大学洛杉矶分校SPOTRIAS中心的三个研究项目的早期患者筛查，以及加州大学洛杉矶分校医学中心和加州大学洛杉矶分校中风网络医院的其他急性中风临床研究工作。这一目标将通过促进患者快速识别、同意方法、研究招募、登记和纵向后续评估来实现。有针对性的计划将促进招募大量女性、西班牙裔美国人、非裔美国人和其他少数群体。

DESCRIPTION (provided by the applicant): This mission-critical Core will facilitate rapid presentation, assessment, and treatment of acute stroke patients, assuring rapid recruitment of patients for the clinical research studies in Projects 1-3, and ensuring a minimum of 12 patients will be treated with IV TPA within 2 hrs. of onset in each Award year. The Patient Access Core's mission will be achieved through four specific aims. Aim 1 is to educate individuals at risk in the catchment areas of UCLA Medical Center, UCLA Stroke Network Hospitals, and throughout the City of Los Angeles regarding stroke warning signs, steps to take if symptoms occur, and the importance of early treatments for brain attack. This aim will be accomplished through lectures, outreach programs, health fairs, and additional educational programs in UCLA Medical Center and UCLA Stroke Network Hospital catchment areas, and throughout Los Angeles. Aim 2 is to educate prehospital care personnel in the catchment areas of UCLA Medical Center UCLA Stroke Network Hospitals, and throughout the City of Los Angeles regarding stroke recognition, pre-hospital stroke treatment, field pre-notification of receiving hospitals, and the importance of rapid transport. This aim will be accomplished by educating paramedics citywide in the use of the Los Angeles Prehospital Stroke Screen (LAPSS) and the Los Angeles Motor Scale (LAMS), and by design, validation, and dissemination of a dispatcher version of the LAPSS. Aim 3 is to optimize rapid Emergency Department and in-hospital management of acute stroke patients at UCLA Medical Center, UCLA Stroke Network Hospitals, and throughout the City of Los Angeles. This aim will be achieved by expanding rapid response acute stroke team activities at UCLA Medical Center and UCLA Network Stroke hospitals. Aim 4 is to ensure early patient screening for participation in the three UCLA SPOTRIAS Center research Projects, and additional acute stroke clinical research endeavors at UCLA Medical Center and UCLA Stroke Network Hospitals. This aim will be achieved by facilitating rapid patient identification, approach for consent, study recruitment, enrollment and longitudinal follow-up evaluations. Targeted programs will promote the recruitment of substantial cohorts of women, Hispanic-Americans, African-Americans, and other minority populations.