ASCB Summer Meeting: Coordinating the Events of Directed

ASCB 夏季会议：协调指导活动

• 批准号: 7000744
• 负责人: Clare Michal Waterman
• 金额: $ 3.46万
• 依托单位: AMERICAN SOCIETY FOR CELL BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7000744
• 关键词: biological signal transduction; biophysics; cell motility; meeting /conference /symposium; molecular biology; travel

DESCRIPTION (provided by applicant): This meeting "Systems Integration in Directed Cell Motility" will be sponsored by the American Society of Cell Biology (ASCB). Topics of ASCB summer meetings are proposed by ASCB members and selected by a committee based on significance, timeliness, interest, and strengths of the organizers and potential speakers. The meeting will be held at the University of Washington, Seattle, WA on July 27-30, 2005. The directed migration of cells involves the complex coordination of multiple cellular signaling, cytoskeletal and adhesion systems in a self-perpetuating cycle. In the past, many of the systems of the cell motility cycle have, in large part, been studied in isolation. The fruits of these labors have established a broader knowledge base, making cross-talk between these molecular systems evident. As such, understanding how these cellular components are integrated and coordinated needs to be further encouraged. Additionally, there have been great technical advances that have contributed to progress in our understanding of each motility sub-system. For a field currently poised to advance at high speed, it is critical that investigators interact regularly to discuss recent advances vis a vis previous paradigms and future developments. Thus, we have organized a meeting that encourages the cross-fertilization of knowledge from research in each of these areas, with the goal to promote more global thinking about how the mechanical and signaling systems of cell motility are integrated and coordinated. The meeting will include talks on molecular mechanisms, biophysics, and signal transduction, as well as highlights of newly developed technologies that have moved the area along significantly in recent years. The presentations will be delivered by a mixture of invited speakers and speakers selected from submitted abstracts. The latter will be primarily young investigators, while the former will be visionaries giving presentations balanced between new results and general perspectives. Posters sessions will foster one-to-one interactions. Understanding directed cell motility from an integrated perspective is of profound and fundamental importance to many physiological functions and pathological states. A more thorough understanding of the processes involved will impact on multiple health-related issues, such as cancer treatment, wound recovery, and anti-inflammatory therapy.

描述(申请人提供)：本次会议“定向细胞运动中的系统集成”将由美国细胞生物学学会(ASCB)赞助。ASCB夏季会议的议题由ASCB成员提出，并由一个委员会根据组织者和潜在演讲者的重要性、及时性、兴趣和优势来选择。会议将于2005年7月27-30日在华盛顿州西雅图的华盛顿大学举行。细胞的定向迁移涉及多个细胞信号、细胞骨架和黏附系统在一个自我维持的循环中的复杂协调。在过去，细胞运动周期的许多系统在很大程度上是孤立地研究的。这些工作的成果建立了更广泛的知识基础，使这些分子系统之间的相互作用变得明显。因此，需要进一步鼓励了解这些细胞组成部分是如何整合和协调的。此外，有了巨大的技术进步，促进了我们对每个运动子系统的理解。对于一个目前正准备以高速发展的领域，研究人员定期互动以讨论相对于先前范式和未来发展的最新进展是至关重要的。因此，我们组织了一次会议，鼓励在这些领域的研究中相互交流知识，目的是促进更多关于细胞运动的机械和信号系统如何整合和协调的全球思考。会议将包括关于分子机制、生物物理学和信号转导的演讲，以及近年来在该领域取得重大进展的新开发技术的亮点。演讲将由特邀演讲者和从提交的摘要中挑选的演讲者混合发表。后者将主要是年轻的调查人员，而前者将是有远见的人，在介绍新成果和总体观点之间取得平衡。海报会议将促进一对一的互动。 从综合的角度理解定向细胞的运动对于许多生理功能和病理状态具有深远而基本的重要性。更透彻地了解所涉及的过程将对多种与健康相关的问题产生影响，如癌症治疗、伤口愈合和抗炎治疗。