2005 Salivary Glands & Exocrine Secretion

描述(申请人提供)：本申请旨在为2005年2月6-11日在加利福尼亚州文图拉市四点喜来登港口举行的关于唾液腺和外分泌的第五届戈登研究会议寻求支持。会议将提供一个论坛，介绍和广泛讨论在理解唾液和相关外分泌腺发育、功能和功能障碍的分子基础方面的最新进展。本次会议的总主题是腺组织的正常和疾病状态。个别会议将重点介绍关于腺体形态发生和维持的分子和细胞相互作用；蛋白质、液体和电解质分泌；涉及上皮细胞的自身免疫性疾病；细胞内信号的空间组织和极化膜运输；唾液作为诊断工具的使用；以及临床观察到的炎症和腺体功能障碍。主旨演讲将以具有国际地位的知名研究人员为特色，他们围绕组织工程和基因治疗应用领域的总主题，以及探索腺细胞功能的信号网络(约翰·杨纪念讲座)。 在组织这次会议时，确定了广泛的国内和国际发言者，包括有前途的年轻和新成立的研究人员，他们的研究涉及或明显影响对唾液腺和其他外分泌腺的发育和功能的理解。组织团队的目标是鼓励这一重要领域的发展和丰富，并鼓励研究唾液腺的新战略。

DESCRIPTION (provided by applicant): This application seeks support for the fifth Gordon Research Conference on Salivary Glands and Exocrine Secretion to be held February 6-11, 2005 at the Four Points Sheraton Harbortown in Ventura, California. The conference will provide a forum for presentation and extensive discussion of the most recent progress in understanding the molecular basis of development, function and dysfunction of salivary and related exocrine glands. The general theme of this conference is normal and disease states of glandular tissues. Individual sessions will highlight new insights concerning molecular and cellular interactions underlying the glandular morphogenesis and maintenance; protein, fluid and electrolyte secretion; autoimmune diseases involving epithelia; spatial organization of intracellular signaling and polarized membrane trafficking; use of saliva as a diagnostic tool, and clinically observed inflammation and glandular dysfunction. Keynote addresses will feature established investigators of international stature who encompass the general theme in the areas of the application of tissue engineering and gene therapy, and signaling networks in exploring glandular cell function (The John Young Memorial Lecture). In organizing this conference, a broad range of national and international speakers has been identified with the inclusion of promising young and newly established investigators whose research either addresses or clearly impacts on the understanding of the development and function of salivary and other exocrine glands. It is the goal of the organizing team to encourage both growth and enrichment of this important field and to stimulate new strategies for studying salivary glands.