International Conference on Cell and Molecular Biology of Chlamydomonas

描述（由申请人提供）：本提案请求支持将于2006年5月9日至14日在俄勒冈州波特兰举行的第12届衣原体细胞和分子生物学国际会议。自1983年成立以来，这个两年一度的会议汇集了来自世界各地（北美，亚洲，欧洲和澳大利亚）的不同领域和学科（细胞生物学，遗传学，生物化学，生物物理学，植物生理学和基因组学）的研究人员，讨论了与这种生物体进行的各种研究项目。衣原体一直是研究细胞和分子生物学中各种主题的最受欢迎的生物体。例如，我们对真核生物鞭毛和基体的了解，大部分来自对衣原体野生型和瘫痪或无鞭毛突变体的研究，我们对光合作用和核/叶绿体遗传相互作用的了解也大部分来自衣原体。最近的工作突出了衣原体研究鞭毛和基体的重要性。衣原体的研究使人们对纤毛在多囊肾病、视网膜变性、早期发育和肥胖中的作用有了深入的了解。这为衣藻工作者提供了获取新技术和新想法信息的机会。

DESCRIPTION (provided by applicant): This proposal requests support for the 12th International Conference on the Cell and Molecular Biology of Chlamydomonas, to be held in Portland Oregon, on May 9-14, 2006. Since its inception in 1983 this now biennial conference has brought together investigators from different fields and disciplines (cell biology, genetics, biochemistry, biophysics, plant physiology.and genomics) from around the world (North America, Asia, Europe and Australia) to discuss a variety of research projects being performed with this organism. Chlamydomonas has been a favorite organism for studying a variety of topics in cell and molecular biology. Much of what we know about the eukaryotic flagellum and basal bodies, for example, comes from studies of wild- type and paralyzed or aflagellate mutants of Chlamydomonas, and much of what we know about photosynthesis and nuclear/chloroplast genetic interactions comes from Chlamydomonas as well. Recent work has highlighted the importance of Chlamydomonas for studying flagella and basal bodies. Work in Chlamydomonas has lead to insights of the role of cilia in polycystic kidney disease, in retinal degeneration, in early development, and in obesity. This provides a chance for workers in Chlamydomonas to gain information on new techniques and ideas.