International Conference on Cell and Molecular Biology of Chlamydomonas

描述(由申请人提供)：本提案请求支持将于2006年5月9-14日在俄勒冈州波特兰举行的第12届衣藻细胞和分子生物学国际会议。自1983年成立以来，这个现在每两年举行一次的会议聚集了来自世界各地(北美、亚洲、欧洲和澳大利亚)的不同领域和学科(细胞生物学、遗传学、生物化学、生物物理学、植物生理学和基因组学)的研究人员，讨论正在对这种微生物进行的各种研究项目。衣藻一直是研究细胞和分子生物学中各种主题的热门生物。例如，我们对真核生物鞭毛和基体的大部分了解来自于对衣藻野生型和瘫痪或滞留突变体的研究，我们对光合作用和核/叶绿体遗传相互作用的许多了解也来自衣藻。最近的工作强调了衣藻对研究鞭毛和基底体的重要性。衣藻的研究使人们对纤毛在多囊肾病、视网膜退化、早期发育和肥胖中的作用有了深入的了解。这为衣藻属的工人提供了一个获得新技术和新想法的机会。

DESCRIPTION (provided by applicant): This proposal requests support for the 12th International Conference on the Cell and Molecular Biology of Chlamydomonas, to be held in Portland Oregon, on May 9-14, 2006. Since its inception in 1983 this now biennial conference has brought together investigators from different fields and disciplines (cell biology, genetics, biochemistry, biophysics, plant physiology.and genomics) from around the world (North America, Asia, Europe and Australia) to discuss a variety of research projects being performed with this organism. Chlamydomonas has been a favorite organism for studying a variety of topics in cell and molecular biology. Much of what we know about the eukaryotic flagellum and basal bodies, for example, comes from studies of wild- type and paralyzed or aflagellate mutants of Chlamydomonas, and much of what we know about photosynthesis and nuclear/chloroplast genetic interactions comes from Chlamydomonas as well. Recent work has highlighted the importance of Chlamydomonas for studying flagella and basal bodies. Work in Chlamydomonas has lead to insights of the role of cilia in polycystic kidney disease, in retinal degeneration, in early development, and in obesity. This provides a chance for workers in Chlamydomonas to gain information on new techniques and ideas.