2006 Gordon Research Conference on Signal Transduction By Engineered ECM

描述（由申请人提供）：这是一个会议资助申请，请求支持第四届戈登研究会议的信号转导工程细胞外基质。这次会议将于2006年7月2日至7日在康涅狄格州新伦敦的康涅狄格学院举行。主席为Michael Sheetz博士，副主席为Molly Shoichet博士。会议将重点关注细胞外基质（ECM）和生长因子在修复和替换因疾病或损伤而丢失或受损的组织中的聚合作用。分析和操纵这些系统的系统生物工程方法将在本次会议中得到强调，与本系列的前两次会议相比，这是会议的一个重要新组成部分。在这些情况下，将有最先进的讨论，未发表的研究信号转导，生长因子和ECM调节细胞命运的机制，以及它们在组织再生和工程中的应用。该计划将包括口头会议（每个有三到四个发言者和一个讨论领导者），以及海报会议（大多数参与者将被期望提出海报）。按照传统标准，会议规模较小（约130名与会者），但与会者将被挑选出来，以确保代表学术和政府机构以及小型和大型生物技术公司的初级和高级研究人员的多样化群体的出席。学生和博士后研究员将被鼓励参加，并在每个会议至少有一个发言者将是一个初级研究员。通过这种方式，会议将为长期跨学科互动的发展提供一个平台，并使学生和年轻的专业人士接触到信号转导，分子和细胞生物学，生物材料和组织工程融合的最新想法和机会。将作出特别努力，利用所要求的财政支助，便利妇女和少数民族出席和参与这次会议。

DESCRIPTION (provided by applicant): This is a conference grant application requesting support for the fourth Gordon Research Conference on Signal Transduction By Engineered Extracellular Matrices. This meeting will be held July 2-7, 2006 at Connecticut College, New London, Connecticut. The Chair will be Dr. Michael Sheetz and the Vice-Chair will be Dr. Molly Shoichet. The conference will focus on the converging roles of the extracellular matrix (ECM) and growth factors for the repair and replacement of tissue lost or damaged due to disease or injury. Systems bioengineering approaches to analyzing and manipulating these systems will be emphasized in this meeting, and this represents a major new component of the meeting, as compared to the previous two conferences in this series. In these contexts, there will be discussion of the state of the art, unpublished research in signal transduction, the mechanisms by which growth factors and the ECM regulate cell fate, and their application to tissue regeneration and engineering. The program will include oral sessions (each with three to four speakers and a discussion leader), as well as poster sessions (most participants will be expected to present a poster). The meeting will be small by conventional standards (approximately 130 participants), but participants will be selected to insure attendance by a diverse group of junior and senior investigators representing academic and government institutions, as well as small and large biotechnology companies. Students and postdoctoral fellows will be encouraged to attend, and at least one speaker in each session will be a junior investigator. In this way the meeting will provide a platform for the development of long term interdisciplinary interactions, and expose students and young professionals to the latest ideas and opportunities at the confluence of signal transduction, molecular and cellular biology, biomaterials and tissue engineering. A special effort will be made to use the financial support requested to facilitate the attendance and participation of women and minorities in this meeting.