Gordon Conference: Cancer Genetics and Epigenetics 2003

描述（由申请人提供）：本申请是为一个名为“癌症遗传学和表观遗传学”的会议提供部分资金，该会议将于2003年1月中旬在加州文图拉的喜来登海港城举行，由戈登研究会议（GRC）主持。 这将是第四届两年一次的GRC会议，在这个领域特别令人兴奋的时刻。 这次会议所涉及的各个领域的工作都在不断取得进展。 这使得研究人员之间的沟通变得更加重要。 在这次会议上，与会者（最多130人）将讨论癌症研究的选定方面和相关的基本遗传/表观遗传机制，讨论当前主题的演讲，评论海报演讲，并开展非正式讨论。 会议将有9个演讲者会议和每日海报会议。 将从提交的摘要中选出海报介绍以及9名以上的发言者。 因此，本次会议将为年轻的研究人员和最新的数据提供一个很好的展示，并邀请国际知名的资深科学家参加。 在这个系列会议的传统中，将强调正式讨论，每次演讲后留出15-20分钟进行辩论。 这次会议将为从事癌症分子生物学研究的人员和从事基因调控基本机制研究的人员提供一个信息交流的论坛。 根据表观遗传基因调控和癌症和癌症前体组织中DNA损伤的分子反应的统一主题，编写了科学讲座的大纲时间表。 这些讲座将涵盖肿瘤抑制和癌基因功能，基因沉默的DNA甲基化，基因组印记和染色质改变，DNA修复和重组的选择方面。 将有一个会议处理这些相同的主题在分子流行病学的设置，和两个会议将处理这些主题在乳腺癌和血液癌症。 最近的发现继续揭示连接这些领域的机制，因此我们预计研究人员之间的相互作用将产生协同进步。

DESCRIPTION (provided by applicant): This application is for partial funding of a conference called "Cancer Genetics and Epigenetics" to be held under the auspices of the Gordon Research Conference (GRC) in mid-January 2003 at the Sheraton Harbortown, Ventura, California. This will be the fourth biennial GRC conference on this topic during a particularly exciting time for the field. Work in all areas covered by this conference is progressing at an ever-increasing pace. This makes communication between researches ever more essential. At this conference, the attendees (130 maximum) working on selected aspects of cancer research and pertinent basic genetic/epigenetic mechanisms will debate presentations on current topics, critique poster presentations, and develop informal discussions. The meeting will feature nine speaker sessions and daily poster sessions. Poster presentations, as well as more than nine of the speakers, will be chosen from the submitted abstracts. Therefore, this conference will provide a good showcase for younger investigators and late-breaking data, as well as featuring internationally renowned senior scientists. In the tradition of this conference series, there will be emphasis on formal discussion, with 15-20 minutes set aside for debate after each talk. This conference will provide a forum for exchange of information between investigators working on the molecular biology of cancer and those working on basic mechanisms of gene regulation. An outline schedule of scientific talks has been prepared based on the unifying themes of epigenetic gene regulation and the molecular responses to DNA damage in cancers and in cancer precursor tissues. These talks will cover selected aspects of tumor suppressor and oncogene function, gene silencing by DNA methylation, genomic imprinting and chromatin alterations, DNA repair and recombination. There will be one session dealing with these same topics in the setting of molecular epidemiology, and two sessions will deal with these topics in breast cancer and hematological cancers. Recent discoveries continue to uncover mechanisms linking these areas, so we expect that cross talk among investigators will yield synergistic advances.