RENOVATIONS FOR AUTOCLAVE SUPPORT SERVICE

高压灭菌器改造支持服务

• 批准号: 6755689
• 负责人: NORMAN H EDELMAN
• 金额: $ 40万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6755689
• 关键词: SCID mouse; animal care; animal welfare research; athymic mouse; biomedical equipment purchase; building /facility design /renovation; genetically modified animals; health science research support; laboratory mouse; nonbiomedical equipment; veterinary science

DESCRIPTION (provided by applicant): The general objective of this project is to provide support and care for the use of transgenic, SCID, knockout, immunocompromised and pathogen free mice at the Stony Brook University (SBU). The institution has both short term and long-term goals to improve animal care and services for the faculty. This grant will purchase equipment, and perform minor renovations for equipment installation, to upgrade autoclave support services in the Health Sciences Center - Division of Laboratory Animal Resources. Eighteen basic and clinically applied research laboratories, who conduct research in gene identification, mapping, analysis and regulation; bacterial and viral receptor regulation; targeted gene therapy; infectious disease pathogenesis; oncology; cerebral amyloid angiopathy; vaccine development; and membrane transport, currently house maximum isolation rodents who require sterilized equipment. The grant will purchase one 99 cu. ft, double door autoclave and two clean steam generators. Minor renovations in existing autoclave and mechanical support areas are required for equipment installation. This support equipment will improve the care of pathogen free animals and address expanding research program needs by providing essential sterilized equipment for maximum isolation housing and reducing occupational health risks and labor costs for animal care personnel through centralization of autoclaving service.

描述（由申请人提供）： 该项目的总体目标是为斯托尼布鲁克大学（SBU）使用转基因、SCID、基因敲除、免疫功能低下和无病原体的小鼠提供支持和护理。该机构有短期和长期目标，以改善动物护理和服务的教师。该补助金将用于购买设备，并对设备安装进行小型翻新，以升级健康科学中心-实验室动物资源部的高压灭菌器支持服务。18个基础和临床应用研究实验室进行基因鉴定、绘图、分析和调节;细菌和病毒受体调节;靶向基因治疗;传染病发病机理;肿瘤学;脑淀粉样血管病;疫苗开发;和膜运输等研究，目前最大限度地隔离需要消毒设备的啮齿动物。 这笔赠款将购买一个99 cu。英尺，双门高压灭菌器和两个干净的蒸汽发生器。需要对现有的高压灭菌器和机械支持区进行小规模翻修，以安装设备。该支持设备将改善无病原体动物的护理，并通过为最大隔离舍提供必要的灭菌设备来满足不断扩大的研究项目需求，并通过集中高压灭菌服务降低职业健康风险和动物护理人员的劳动力成本。