Pilot Study of Automated Surveillance to Measure Burden

自动监测衡量负担的试点研究

• 批准号: 7048770
• 负责人: Paul Evan Kilgore
• 金额: $ 4.99万
• 依托单位: INTERNATIONAL VACCINE INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7048770
• 关键词: India; Internet; Retroviridae disease; Rotavirus; automated medical record system; clinical research; communicable disease diagnosis; computer human interaction; computer system design /evaluation; diarrhea; epidemiology; feces analysis; field study; hospital utilization; human population study; human subject; infant human (0-1 year); international cooperation; patient /disease registry; polymerase chain reaction; preschool child (1-5); telecommunications

DESCRIPTION: Rotavirus is the most common cause of diarrhea among children < 5 years of age and is responsible for an estimated 440,000 deaths each year. Most of these deaths occur in developing countries and India accounts for approximately 100,800 (23%) rotavirus-associated deaths annually. We hypothesize that a phone- and web-based case reporting system will be well-accepted by clinic and hospital based clinicians and laboratory staff. We also hypothesize that introduction of this system will provide a robust method for highly efficient disease reporting and monitoring of diarrhea and rotavirus incidence among the target population of children < 5 years of age. The specific aims are to: 1. Establish the feasibility of implementing a phone/web-based disease reporting system. We will conduct baseline and post-introduction field assessments of system acceptability, ease of use, and reporting accuracy compared with use of traditional paper-based surveillance reports among hospital-based pediatric care providers. We will identify methods to optimize use and introduction of the phone/web-based surveillance system in areas with limited telecommunications and health-care infrastructure. 2. Determine the burden hospitalizations among children < 5 years of age in the study population for acute diarrhea. Children who attend hospitals with acute diarrhea will be clinically evaluated and a fecal specimen will be collected for rotavirus antigen detection testing using a commercially-prepared assay. Hospital-based clinicians will report patients with diarrhea and children with laboratory-confirmed rotavirus diarrhea via the phone/web-based reporting system. 3. Determine the methodologic appropriateness and accuracy of measuring population-based incidence rates for alll-cause diarrhea hospitalizations and rotavirus diarrhea hospitalizations among sub-district populations within the field site. We will analyze ICD-10 hospital discharge codes and review pediatric departments logbooks to assess the proportion of children with diarrhea who are captured in the phone/web-based surveillance system. We will calculate the proportion of children with an adequate fecal specimen that is collected and tested for rotavirus. We will assess the potential use of the phone/web-based case reporting system for measuring the impact of health interventions including vaccines.

描述：轮状病毒是<5岁儿童腹泻的最常见原因，每年估计造成440,000人死亡。这些死亡中的大多数发生在发展中国家，印度每年约有100,800（23％）轮状病毒相关的死亡。我们假设基于电话和网络的病例报告系统将受到诊所和医院临床医生和实验室人员的良好认可。我们还假设，该系统的引入将为高效的疾病报告和监测腹泻和轮状病毒发病率的高效疾病报告提供强大的方法。具体目的是：1。建立实施基于电话/网络的疾病报告系统的可行性。与在基于医院的儿科护理提供者中使用传统的基于纸张的监视报告相比，我们将对系统可接受性，易用性和报告准确性进行基线和引入后现场评估。我们将确定在电信和医疗保健基础设施有限的领域优化使用和引入基于电话/网络的监视系统的方法。 2。确定急性腹泻的研究人群中5岁儿童的负担。将对患有急性腹泻的医院的儿童进行临床评估，并使用商业准备的测定法收集粪便标本进行轮状病毒抗原检测测试。基于医院的临床医生将通过电话/基于Web的报告系统报告患有腹泻的患者和实验室确认的轮状病毒腹泻儿童。 3.确定全因腹泻住院和轮状病毒腹泻住院的方法学适当性和基于人群的发病率的准确性。我们将分析ICD-10医院出院法规并审查小儿部门日志，以评估在电话/基于网络的监视系统中被捕获的腹泻儿童的比例。我们将计算有足够的粪便标本的儿童的比例，该标本已收集并测试轮状病毒。我们将评估基于电话/网络的病例报告系统的潜在用途，以测量包括疫苗在内的健康干预措施的影响。