FAME 1 - Eye

糖尿病是导致成年人失明的最常见原因之一。视力丧失是不可逆转的，是糖尿病最可怕的并发症。一种名为非诺贝特的降血脂药物在澳大利亚有售，已被证明可将2型糖尿病患者的眼睛损伤减少35-40%，并在1型糖尿病动物模型中预防眼睛损伤。本研究将评估非诺贝特对450例早期糖尿病眼损伤的成人1型糖尿病患者的潜在益处。

Diabetes is one of the commonest cause of blindness in adults. Vision loss, which is irreversible, is a most feared complication of diabetes. A blood fat lowering drug called fenofibrate, available in Australia, has been shown to reduce eye damage in people with Type 2 diabetes by 35-40%, and to prevent eye damage in Type 1 diabetic animal models. This study will evaluate the potential benefits of fenofibrate in 450 adults with Type 1 diabetes who have early diabetic eye damage.