Development of new catalytic methods for the efficient construction of natural product-inspired 3D scaffolds

开发新的催化方法以有效构建天然产物启发的 3D 支架

• 批准号: 2672142
• 金额: --
• 依托单位: University of Nottingham
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2672142
• 关键词: Development; new; catalytic; methods; efficient

This PhD project aims to develop new catalytic synthetic methods for the efficient construction of natural product-inspired 3D scaffolds. The research will explore the application of recently discovered C-H and X-H bond activation using metallocarbenoids to generate SP3-rich cyclic and spirocyclic structures. The application of this methodology to the synthesis of biologically active natural and non-natural products will also be explored.

该博士项目旨在开发新的催化合成方法，用于高效构建天然产物启发的3D支架。该研究将探索最近发现的C-H和X-H键活化的应用，使用类卡宾生成富含SP3的环状和螺环结构。还将探讨这种方法在合成具有生物活性的天然和非天然产物中的应用。