Crops and Soil - EASTBIO Dynamic ubiquitin signalling coordinates transcriptional reprogramming in plant immunity

基因表达的动态调控对所有生物都至关重要，使它们能够对不断变化的环境做出反应。植物细胞在应对病原体攻击时表现出戏剧性的转录组重编程，确保免疫反应优先于正常细胞功能。免疫激素水杨酸（SA）在这一过程中起着不可或缺的作用，建立持久的疾病抵抗未来病原体的攻击。影响SA信号的化学和遗传方法已经被开发出来，以对抗威胁未来粮食安全的经济上昂贵的植物病害。然而，这些保护战略往往在环境上不可持续，或对植物生长和产量有不利影响。了解SA如何重编程转录组以建立持久的免疫，将使作物保护的改进可持续技术的设计迫在眉睫。

Dynamic regulation of gene expression is vital for all organisms and enables them to respond to the ever-changing environment. Plant cells display dramatic reprogramming of the transcriptome in response to pathogen attack, ensuring prioritisation of immune responses over normal cellular functions. The immunizing hormone salicylic acid (SA) plays indispensable roles in this process, establishing long-lasting disease resistance against future pathogen attack. Chemical and genetic approaches that impinge on SA signalling have been developed to combat economically costly plant diseases that threaten future food security. However, these protection strategies are often environmentally unsustainable or have penalties on plant growth and yield. Understanding how SA reprograms the transcriptome to establish durable immunity will enable the urgent design of improved sustainable technologies for crop protection.