Crops and Soil - EASTBIO Dynamic ubiquitin signalling coordinates transcriptional reprogramming in plant immunity

作物和土壤 - EASTBIO 动态泛素信号传导协调植物免疫中的转录重编程

• 批准号: 2672570
• 金额: --
• 依托单位: University of Edinburgh
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2672570
• 关键词: Crops; Soil; EASTBIO; Dynamic; ubiquitin

Dynamic regulation of gene expression is vital for all organisms and enables them to respond to the ever-changing environment. Plant cells display dramatic reprogramming of the transcriptome in response to pathogen attack, ensuring prioritisation of immune responses over normal cellular functions. The immunizing hormone salicylic acid (SA) plays indispensable roles in this process, establishing long-lasting disease resistance against future pathogen attack. Chemical and genetic approaches that impinge on SA signalling have been developed to combat economically costly plant diseases that threaten future food security. However, these protection strategies are often environmentally unsustainable or have penalties on plant growth and yield. Understanding how SA reprograms the transcriptome to establish durable immunity will enable the urgent design of improved sustainable technologies for crop protection.

基因表达的动态调控对所有生物体都至关重要，使它们能够对不断变化的环境做出反应。植物细胞响应病原体攻击显示转录组的戏剧性重编程，确保免疫反应优先于正常细胞功能。免疫激素水杨酸（SA）在这一过程中起着不可或缺的作用，建立了持久的抗病能力，以抵御未来的病原体攻击。已经开发出了影响SA信号的化学和遗传方法，以防治威胁未来粮食安全的经济上昂贵的植物疾病。然而，这些保护战略往往在环境上是不可持续的，或者对植物生长和产量有不利影响。了解SA如何重新编程转录组以建立持久的免疫力，将有助于紧急设计改进的可持续作物保护技术。