Novel enzymatic modifications of polysaccharides for new health and personal care products

用于新型健康和个人护理产品的多糖的新型酶促修饰

• 批准号: 2680899
• 金额: --
• 依托单位: University of York
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2680899
• 关键词: Novel; enzymatic; modifications; polysaccharides; new

In this interdisciplinary project, we propose to use 'omics technologies, bioinformatics and molecular biology to discover highly performing chitin/chitosan transforming enzymes to provide 'natural' materials with improved material properties further widening their use as inherently sustainable home product additives. The student will undertake experiments to produce recombinant forms of these enzymes using state of the art bacterial and yeast expression systems. Target proteins will be studied for their biochemical action on chitin/chitosan and how these adapt their material properties in collaboration with Prof Justin Perry in the Department of Applied Sciences at Northumbria University, Newcastle.

在这个跨学科项目中，我们建议利用组学技术、生物信息学和分子生物学来发现高性能的甲壳素/壳聚糖转化酶，以提供具有改进的材料性能的“天然”材料，进一步扩大其作为本质上可持续的家用产品添加剂的用途。学生将进行实验，使用最先进的细菌和酵母表达系统生产这些酶的重组形式。我们将与纽卡斯尔诺森比亚大学应用科学系的贾斯汀·佩里教授合作，研究目标蛋白对甲壳素/壳聚糖的生化作用，以及它们如何调整其材料特性。