Novel enzymatic modifications of polysaccharides for new health and personal care products

在这个跨学科的项目中，我们建议使用“组学”技术，生物信息学和分子生物学来发现高性能的几丁质/壳聚糖转化酶，以提供具有改进材料性能的“天然”材料，进一步扩大其作为内在可持续的家用产品添加剂的用途。学生将进行实验，利用最先进的细菌和酵母表达系统生产这些酶的重组形式。与纽卡斯尔诺森比亚大学应用科学系的Justin Perry教授合作，将研究目标蛋白在几丁质/壳聚糖上的生化作用，以及这些蛋白如何改变其材料特性。

In this interdisciplinary project, we propose to use 'omics technologies, bioinformatics and molecular biology to discover highly performing chitin/chitosan transforming enzymes to provide 'natural' materials with improved material properties further widening their use as inherently sustainable home product additives. The student will undertake experiments to produce recombinant forms of these enzymes using state of the art bacterial and yeast expression systems. Target proteins will be studied for their biochemical action on chitin/chitosan and how these adapt their material properties in collaboration with Prof Justin Perry in the Department of Applied Sciences at Northumbria University, Newcastle.