European mistletoe (Viscum album) as a case study for understanding the regulation of host-parasite relationships

欧洲槲寄生（Viscum album）作为了解宿主与寄生虫关系调节的案例研究

• 批准号: 2696837
• 金额: --
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2696837
• 关键词: European; mistletoe; Viscum; album; case

Parasites, which live on or in a host organism to the host's detriment, have widespread ecological, evolutionary, and socioeconomic consequences. To persist, any parasite must exploit its host's resources enough to live, without killing its host before successful reproduction and transmission. In other words, damage to the host (virulence) and transmission must be moderated to avoid local parasite extinction. We are still uncovering how host-parasite systems are regulated in this way and questioning how universally such mechanisms determine the outcome for parasite and host. Understanding what drivers tip the balance towards parasite or host is key to controlling parasites which are important to society. Such control is as essential as ever given the continued burden of disease we face.

寄生在寄主身上或体内对寄主有害的寄生虫具有广泛的生态、进化和社会经济后果。为了生存，任何寄生虫都必须充分利用宿主的资源，在成功繁殖和传播之前不杀死宿主。换句话说，必须减缓对宿主的损害（毒力）和传播，以避免当地寄生虫灭绝。我们仍然在揭示宿主-寄生虫系统是如何以这种方式调节的，并质疑这种机制如何普遍地决定寄生虫和宿主的结果。了解是什么驱动因素使平衡倾向于寄生虫或宿主是控制对社会重要的寄生虫的关键。鉴于我们面临的持续疾病负担，这种控制与以往一样至关重要。