Fetal middle cerebral artery Doppler to time second and subsequent fetal transfusions for red cell alloimmunisation.

胎儿大脑中动脉多普勒检查第二次和随后的胎儿输血以进行红细胞同种免疫。

• 批准号: nhmrc : 627195
• 负责人: Dr Chad Andersen
• 金额: $ 29.98万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/fetal-middle-cerebral-cell-alloimmunisation/82303
• 关键词: Fetal; middle; cerebral; artery; Doppler

Blood group incompatability between a mother and her unborn baby can result in the production of antibodies that can damage the baby's red blood cells, causing anaemia. Treatment involves a procedure to transfuse blood to the baby while in the mother's uterus, which often needs to be repeated several times during a pregnancy. This randomised trial will assess if an ultrasound examination can be used to time second or subsequent fetal transfusions, and the impact this has on infant health.

母亲和未出生的婴儿之间的血型不相容会导致产生抗体，从而破坏婴儿的红细胞，导致贫血。治疗包括在母亲子宫内给婴儿输血，在怀孕期间经常需要重复几次。这项随机试验将评估超声波检查是否可以用于第二次或随后的胎儿输血时间，以及这对婴儿健康的影响。