Fetal sex: an important determinant of the placental transcriptome
Fetal sex: an important determinant of the placental transcriptome
批准号:
nhmrc : 1059120
负责人:
A/Pr Cheryl Shoubridge
金额:
$36.91万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
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英文摘要
There are fetal sex differences in pregnancy outcomes that place boys at greater risk than girls. These are likely caused by genetic differences in the placenta. We will use 21st century gene sequencing technology to obtain the complete sequence of placental genes in early pregnancy and normal term placenta to determine what the genetic differences are between male and female placentas. This may be important in developing future sex specific therapeutics for babies in the neonatal nursery.
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Improving the phenotypic severity of intellectual disability and seizures caused by expanded polyalanine tract mutations in the ARX homeobox transcription factor.
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批准号:nhmrc : 1099538
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项目类别:Project Grants
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资助金额:$46.9万
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财政年份:2016
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负责人:A/Pr Cheryl Shoubridge
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依托单位:
Improving the phenotypic severity of intellectual disability and seizures caused by expanded polyalanine tract mutations in the ARX homeobox transcription factor.
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批准号:nhmrc : GNT1099538
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项目类别:Project Grants
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资助金额:$68.36万
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财政年份:2016
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负责人:A/Pr Cheryl Shoubridge
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依托单位:
Investigating the pathogenic mechanisms of mutations in the ARX homeobox transcription factor
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批准号:nhmrc : 1063025
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项目类别:Project Grants
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资助金额:$39.76万
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财政年份:2014
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负责人:A/Pr Cheryl Shoubridge
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依托单位:
Investigating the pathogenic role of polyalanine tract expansion mutations in the ARX homeobox transcription factor.
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批准号:nhmrc : 1002732
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项目类别:NHMRC Project Grants
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资助金额:$36.38万
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财政年份:2011
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负责人:A/Pr Cheryl Shoubridge
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依托单位:
Investigating the pathogenic mechanism of mutations in IQSEC2 causing non-syndromic intellectual disability.
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批准号:nhmrc : 1006586
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项目类别:NHMRC Project Grants
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资助金额:$29.94万
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财政年份:2011
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负责人:A/Pr Cheryl Shoubridge
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依托单位:
Investigation of the pathogenesis of expanded polyalanine tract mutations of the ARX
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批准号:nhmrc : 408402
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项目类别:Early Career Fellowships
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资助金额:$22.41万
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财政年份:2007
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负责人:A/Pr Cheryl Shoubridge
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依托单位:
国内基金
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