An ERP Analysis of Cognition After Emotion Regulation

情绪调节后认知的 ERP 分析

• 批准号: 7220999
• 负责人: CHRISTEN M DEVENEY
• 金额: $ 2.25万
• 依托单位: HARVARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-22 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7220999
• 关键词: attention; behavioral /social science research tag; brain electrical activity; brain mapping; clinical research; cognition; emotional adjustment; evoked potentials; human subject; major depression; neural information processing; predoctoral investigator; prefrontal lobe /cortex; psycholinguistics; psychomotor reaction time; psychopathology; vocabulary

DESCRIPTION (provided by applicant): Although 85% of mental illnesses (including major depressive disorder (MDD)) are thought to involve dysfunction in emotion regulation (ER) processes, little empirical evidence exists regarding the exact nature of the abnormalities present in these populations. Recent research has linked certain ER strategies with memory impairments. Researchers suggest that "cognitive shortcuts" such as biases and schemas may be used to compensate for those impairments. Because biased cognitive processes are important in the development, maintenance, and exacerbation of depressed mood, it is conceivable that abnormalities in ER may contribute to abnormalities in MDD. In the proposed studies event-related brain potentials will be employed to probe the relationship between ER strategies and information processing. It is predicted that enhancing one's negative emotion will decrease early attention-oriented and increase later elaborative brain activity to negative stimuli, relative to maintaining or suppressing that emotion and relative to maintaining a neutral emotion. Secondly, individuals with MDD are hypothesized to show enhanced brain activity to negative stimuli after enhancing a negative emotion relative to healthy controls.

描述（由申请人提供）：尽管人们认为85％的精神疾病（包括重度抑郁症（MDD））涉及情绪调节过程（ER）过程中的功能障碍，但几乎没有关于这些人群中异常的确切性质的经验证据。最近的研究将某些ER策略与记忆障碍联系起来。研究人员认为，可以使用诸如偏见和模式等“认知快捷方式”来补偿这些障碍。由于偏见的认知过程在情绪低落的发展，维持和加剧中很重要，因此可以想象，ER的异常可能导致MDD异常。在拟议的研究中，将采用与事件相关的大脑电位来探测ER策略与信息处理之间的关系。可以预测，相对于维持或抑制这种情绪和相对于维持中性情绪而言，增强人的负面情绪将减少早期注意力引起的引起注意力，并将后来的详细脑活动增加到负面刺激。其次，假设患有MDD的个体在增强了相对于健康对照组的负面情绪后显示出对负面刺激的增强。