Perfectionism in adolescents with depression

抑郁症青少年的完美主义

• 批准号: 7113523
• 负责人: RACHEL H JACOBS
• 金额: $ 3.94万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7113523
• 关键词: adolescence (12-20); antidepressants; attitude; behavioral /social science research tag; child psychology; clinical trials; cognitive behavior therapy; combination therapy; disease /disorder proneness /risk; fluoxetine; human subject; human therapy evaluation; longitudinal human study; major depression; mental disorder chemotherapy; mental health epidemiology; patient oriented research; placebos; predoctoral investigator; psychopharmacology; relapse /recurrence; serotonin inhibitor; suicide

DESCRIPTION (provided by applicant): The Treatment for Adolescents with Depression Study (TADS) is a randomized controlled trial funded by the National Institute of Mental Health and conducted at 14 sites. A sample of 439 adolescents between 12 and 17 years of age with a diagnosis of major depressive disorder participated in TADS. Participants were randomly assigned to 1 of 4 treatments: cognitive behavior therapy (CBT), fluoxetine (FIX), cognitive behavior therapy in combination with fluoxetine (Combo), or pill placebo (PBO). In addition to primary outcome measures, several additional measures were included in the TADS dataset and will be available for secondary analyses. My research will look at the role of dysfunctional attitudes in the development of adolescent depression. Specifically, I will explore perfectionism as a possible predictor, moderator, and/or mediator of treatment response in terms of depression symptoms and suicidality. Longitudinal data will be available in approximately 1 year and will allow for the testing of models of relations between perfectionism, dysfunctional attitudes, and depression. These findings will contribute to the understanding of cognitive vulnerability for depression and mechanisms of treatment response in depressed adolescents.

描述（由申请人提供）：抑郁症研究青少年的治疗（TADS）是由国家心理健康研究所资助并在14个地点进行的随机对照试验。在12至17岁之间的439名青少年的样本中，诊断为重度抑郁症。将参与者随机分配到4种治疗方法中的1种：认知行为疗法（CBT），氟西汀（FIX），认知行为疗法与氟西汀（组合）或药丸安慰剂（PBO）结合使用。除了主要结果指标外，TADS数据集还包括了一些其他措施，并将用于辅助分析。我的研究将研究功能失调的态度在青春期抑郁症发展中的作用。具体而言，我将在抑郁症状和自杀性方面探索完美主义作为治疗反应的可能预测因素，主持人和/或调解人。纵向数据将在大约1年内提供，并可以测试完美主义，功能障碍态度和抑郁症之间的关系模型。这些发现将有助于理解抑郁症的认知脆弱性和沮丧的青少年治疗反应机制。