Integrative Examination of Comorbidity with ADHD

多动症合并症的综合检查

• 批准号: 7055236
• 负责人: HEATHER E VOLK
• 金额: $ 0.5万
• 依托单位: SAINT LOUIS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2006-07-10
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7055236
• 关键词: alcoholism /alcohol abuse; attention deficit disorder; behavioral /social science research tag; behavioral genetics; child psychology; clinical research; comorbidity; conduct disorder; depression; disease /disorder etiology; disease /disorder proneness /risk; gene environment interaction; health behavior; human data; mathematical model; mental disorder diagnosis; mental health epidemiology; model design /development; molecular genetics; oppositional defiant disorder; predoctoral investigator; psychopathology; smoking; statistics /biometry

DESCRIPTION (provided by applicant): This pre-doctoral research support application is structured to prepare the applicant to compete for a research-oriented faculty position in psychiatric and genetic epidemiology. Specifically, training & supervised research experience will focus on combining epidemiologic, statistic, & behavior genetic methods to study the etiology of child psychiatric disorder co-occurrence. Disorder clustering, severity, shared genetic influence, & outcomes will be examined to assess the relationship of comorbid psychopathology with Attention Deficit Hyperactivity Disorder (ADHD). ADHD is a multi-dimensional disorder characterized by symptoms of hyperactivity, impulsivity, & inattention, thus, externalizing & internalizing disorders may co-occur differentially. Genes or the environment both likely influence the etiology of these disorders & their permutations in different ways. This pre-doctoral fellowship award will allow the applicant to: 1) conduct secondary data analysis of two existing datasets to systematically examine comorbidity with ADHD & influences on disorder clustering employing contemporary statistical methodology & 2) complete coursework & training in these methods, psychiatric epidemiology, & gain an introduction to molecular genetics.

描述(由申请者提供)：这份博士前研究支持申请是为申请者竞争精神病学和遗传流行病学的研究型教职而设计的。具体地说，培训和监督研究经验将侧重于结合流行病学、统计学和行为遗传学方法来研究儿童精神障碍共同发生的病因学。将检查障碍聚集、严重性、共同的遗传影响和结果，以评估共病精神病理与注意缺陷多动障碍(ADHD)的关系。ADHD是一种以多动、冲动和注意力不集中等症状为特征的多维障碍，因此外在性和内在性障碍可以不同地共存。基因或环境都可能以不同的方式影响这些疾病的病因&它们的排列。这一博士前奖学金将允许申请者：1)对现有的两个数据集进行二次数据分析，以系统地检查ADHD的共病情况以及使用当代统计方法对障碍聚集的影响；2)完成这些方法的课程和培训，精神病学流行病学，并获得分子遗传学入门。

项目成果

Comorbidity between ADHD and symptoms of bipolar disorder in a community sample of children and adolescents.

儿童和青少年社区样本中多动症和双相情感障碍症状之间的合并症。

• DOI: 10.1375/183242705774310105
• 发表时间: 2005
• 期刊: Twin research and human genetics : the official journal of the International Society for Twin Studies
• 作者: Reich,Wendy;Neuman,RosalindJ;Volk,HeatherE;Joyner,CynthiaA;Todd,RichardD
• 通讯作者: Todd,RichardD

The XVth World Congress of Psychiatric Genetics, October 7-11, 2007: Rapporteur summaries of oral presentations.

第十五届世界精神病遗传学大会，2007 年 10 月 7-11 日：报告员口头报告摘要。

• DOI: 10.1002/ajmg.b.30711
• 发表时间: 2008
• 期刊: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
• 作者: Alkelai,Anna;Baum,Amber;Carless,Melanie;Crowley,James;Dasbanerjee,Tania;Dempster,Emma;Docherty,Sophia;Hare,Elizabeth;Galsworthy,MichaelJ;Grover,Deepak;Glubb,Dylan;Karlsson,Robert;Mill,Jonathan;Sen,Srijan;Quinones,MarlonP;Va
• 通讯作者: Va

Genetic influences on free and cued recall in long-term memory tasks.

遗传对长期记忆任务中自由回忆和提示回忆的影响。

• DOI: 10.1375/183242706778553462
• 发表时间: 2006
• 期刊: Twin research and human genetics : the official journal of the International Society for Twin Studies
• 作者: Volk,HeatherE;McDermott,KathleenB;Roediger3rd,HenryL;Todd,RichardD
• 通讯作者: Todd,RichardD