PET STUDIES IN ATTENTION DEFICIT DISORDER: ROLE OF DOPAMINE

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to see if there are abnormalities in dopamine, a chemical found in the brain, in people with Attention Deficit Hyperactive Disorder. Dopamine is linked with movement, ability to think or concentrate, and pleasure. A small dose of methylphenidate (a drug which releases dopamine) and a radiotracer, which is a radioactive chemical that indicates how much dopamine is released by your brain when you receive the methylphenidate, are injected into a vein and then a Positron Emission Tomography (PET) camera takes pictures of the movement of the radiotracer in the body.