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PET STUDIES IN ATTENTION DEFICIT DISORDER: ROLE OF DOPAMINE

PET STUDIES IN ATTENTION DEFICIT DISORDER: ROLE OF DOPAMINE
注意力缺陷障碍的宠物研究:多巴胺的作用
批准号:
7375392
负责人:
GENE-JACK WANG
金额:
$0.81万
依托单位国家:
美国
项目类别:
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-12-01 至 2006-11-30

项目摘要

项目成果

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中文摘要
翻译
本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者(PI)可能已经从另一个NIH来源获得了主要资金,因此可以在其他CRISP条目中表示。列出的机构是中心的,不一定是研究者的机构。这项研究的目的是看看多巴胺是否有异常,多巴胺是一种存在于大脑中的化学物质,存在于注意力缺陷多动障碍患者的大脑中。多巴胺与运动、思考或集中注意力的能力以及快乐有关。小剂量的哌醋甲酯(一种释放多巴胺的药物)和放射性示踪剂(一种放射性化学物质,表明当你接受哌醋甲酯时,你的大脑释放了多少多巴胺)被注射到静脉中,然后正电子发射断层扫描(PET)相机拍下放射性示踪剂在体内的运动。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to see if there are abnormalities in dopamine, a chemical found in the brain, in people with Attention Deficit Hyperactive Disorder. Dopamine is linked with movement, ability to think or concentrate, and pleasure. A small dose of methylphenidate (a drug which releases dopamine) and a radiotracer, which is a radioactive chemical that indicates how much dopamine is released by your brain when you receive the methylphenidate, are injected into a vein and then a Positron Emission Tomography (PET) camera takes pictures of the movement of the radiotracer in the body.
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会议论文
PET STUDIES OF COCAINE ABUSE: EFFECTS OF EXPECTATION
CLINICAL TRIAL: BRAIN METABOLIC RESPONSE TO IMAGES OF VIOLENT BEHAVIOR
CLINICAL TRIAL: MEASUREMENT OF DOPAMINE SYSTEMS IN SUBJECTS AT-RISK FOR ALCOHOL
CLINICAL TRIAL: BRAIN DOPAMINE, REWARD AND MOTIVATION IN OBESE SUBJECTS
海外基金