Advanced Vestibular Evoked Myogenic Potential (VEMP) Screening and Testing System

先进的前庭诱发肌源电位（VEMP）筛查和测试系统

• 批准号: 7053708
• 负责人: Edward Miskiel
• 金额: $ 9.99万
• 依托单位: INTELLIGENT HEARING SYSTEMS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7053708
• 关键词: auditory feedback; auditory stimulus; biomedical equipment development; clinical biomedical equipment; clinical research; ear disorder diagnosis; electromyography; evoked potentials; hearing tests; human subject; mass screening; middle childhood (6-11); ototoxin; patient monitoring device; patient oriented research; pediatrics; preschool child (1-5); vestibular apparatus; video recording system

DESCRIPTION (provided by applicant): The objective of this project is to develop a comprehensive and advanced Vestibular Evoked Myogenic Potential (VEMP) testing module as part of an integrated hearing and vestibular assessment ystem that can be used for vestibular screening, testing, ototoxicity monitoring and other related applications. VEMPs are currently acquired using standard Auditory Evoked Potential (AEP) systems which do not provide adequate controls over background EMG activity required to record consistent and valid VEMP responses. The proposed work will develop a module specifically dedicated to VEMP testing with features that are currently unavailable including background EMG monitoring and patient feedback with video display reinforcement for testing children. The module will be implemented in the SmartEP AEP diagnostic testing system as well as a newly developed portable platform to be used for VEMP testing for bedside ototoxicity monitoring and vestibular screening applications. The proposed device will have a direct impact on public health by standardizing the acquisition of VEMP responses, which provide a unique and objective test of saccule function, in an integrated testing module.

描述（由申请人提供）：该项目的目标是开发一种全面且先进的前庭诱发肌源电位（VEMP）测试模块，作为集成听力和前庭评估系统的一部分，可用于前庭筛查、测试、耳毒性监测和其他相关应用。目前使用标准听觉诱发电位 (AEP) 系统获取 VEMP，该系统无法对记录一致且有效的 VEMP 响应所需的背景肌电图活动提供足够的控制。拟议的工作将开发一个专门用于 VEMP 测试的模块，其功能目前不可用，包括背景肌电图监测和患者反馈以及用于测试儿童的视频显示强化。该模块将在 SmartEP AEP 诊断测试系统以及新开发的便携式平台中实施，用于床边耳毒性监测和前庭筛查应用的 VEMP 测试。拟议的设备将通过标准化 VEMP 响应的获取对公共健康产生直接影响，该响应在集成测试模块中提供独特且客观的球囊功能测试。