Development of Novel Ion Selective Biosensors

新型离子选择性生物传感器的开发

• 批准号: 2734001
• 金额: --
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2734001
• 关键词: Development; Novel; Ion; Selective; Biosensors

There is a great need for miniaturised ion sensors for applications ranging from understanding physiology and pathology of the brain (e.g. in epilepsy, brain cancer) to human performance monitoring (e.g. with wearables). The aim of this project is to develop such sensors based on transistors functionalised with ion selective membranes. We will aim to understand the physics of these devices and push them to their performance limits in terms of sensitivity, stability and response time. We will then validate their use in implantable devices using suitable model of neurological disorders.

非常需要用于从理解大脑的生理学和病理学（例如癫痫、脑癌）到人类表现监测（例如使用可穿戴设备）的应用范围的嵌入式离子传感器。该项目的目的是开发基于离子选择性膜功能化的晶体管的传感器。我们的目标是了解这些设备的物理特性，并在灵敏度，稳定性和响应时间方面将它们推向性能极限。然后，我们将使用合适的神经系统疾病模型验证其在植入式器械中的用途。