Nanocoatings for Biomedical Implants

描述（由申请人提供）：拟开发一种羟基磷灰石（HAp）纳米涂层在钛牙种植体上。骨整合在植牙手术中起着至关重要的作用，因为它受到合适的结构材料、设计和手术技术的影响。长期以来，种植体制造商和种植外科专家一直在寻求快速固定和耐用的种植体。所提出的纳米颗粒涂层有望提供良好的附着力，控制相以持久，控制孔径以促进组织生长。该涂层将采用静电喷涂涂层和微波烧结或激光烧结的混合工艺制备。将测量平均孔径、表面粗糙度、相和涂层的附着力。将测试涂层牙种植体的力学性能，包括强度和断裂韧性。所提出的纳米颗粒涂层技术具有沉积速率高、适用于各种复合涂层、对简单和复杂几何结构的兼容性、灵活性和低成本等优点。我们预计，该涂层技术的应用将消除非晶态HAp的形成，而非晶态HAp易溶解于体液中，影响界面粘附。

DESCRIPTION (provided by applicant): It is proposed to develop a nanoparticle coating of hydroxyapatite (HAp) on titanium dental implants. Osseointegration is of critical importance in dental implant surgical operation because it is affected by the proper selection of construction materials, design, and surgical techniques. Fast fixation and durability of dental implants have long been sought by dental implant manufacturers and implant surgical specialists. The proposed nanoparticle coating is expected to provide good adhesion, controlled phases for durability, and controlled pore size for promoting tissue growth. The coating will be fabricated using a hybrid process of electrostatic spray coating and microwave sintering or laser sintering. The average pore size, surface roughness, phase, and the adhesion of the coating will be measured. The mechanical properties, including the strength and the fracture toughness of the coated dental implants, will be tested. The proposed nanoparticle coating technique offers high deposition rate, suitability for various composite coatings, compatibility to simple and complex geometry, flexibility, and low cost. We anticipate that the application of this coating technique will eliminate the formation of amorphous HAp, which is easily dissolved into body fluid and affects the interfacial adhesion.