First-Line Management of Youth Depression: A Randomised Placebo-Controlled Trial of Fluoxetine and Cognitive Behavioural Therapy

这项研究旨在确定当青少年和年轻人到心理健康诊所就诊时，如何最好地治疗他们患有中度到重度抑郁症。目前，对于是否应在心理治疗的同时开始对年轻人进行抗抑郁治疗，还是首先开始单独进行心理治疗，存在相当大的不确定性。这项研究旨在通过实施一项比较两种治疗方法的试验来澄清这一重要问题。

The study aims to establish how to best treat adolescents and young adults when they present to mental health clinics with moderate-to-severe depression. There is, at present, considerable uncertainty as to whether young people should be started on antidepressant treatment at the same time as psychotherapy, or whether psychotherapy alone be commenced first. The study aims to clarify this important issue by implementing a trial that compares both treatment approaches.