Training Program in Signal Transduction and Cancer

描述（由申请人提供）： 本申请是一项请求， 继续资助T32 CA 70085在罗伯特H。Lurie综合癌症 西北大学中心。 癌症中心是由一个支持 NCI的资助（P30 CA 60553）。 此外，癌症中心还收到了 两个孢子赠款[乳腺癌孢子（P50 CA 89018）和前列腺孢子 癌症（P50 CA 90386）]。 信号训练计划 转导和癌症汇集了主要研究人员和 博士后研究员，对激素，受体，生长 因子和信号转导途径。 这是通过以下方式实现的： 组织会议、期刊俱乐部、研讨会和专题讨论会。 这些活动 为分享最新科学成果提供更多机会， 促进更多的互动。 导师都是由国家卫生研究院资助的 他们属于癌症的所有四个基础科学项目 中心： 病毒致癌;肿瘤侵袭、转移和血管生成; 信号转导与癌症;癌症基因与分子调控。 该计划已成功培养了13名博士后研究员，其中包括两名 少数 在过去的五年里， 学员参加 教育活动（实验室会议、期刊俱乐部、研讨会、专题讨论会） 除了他们的实验室研究之外，他们还与该计划有关。 五 学员成功地竞争了校外国家资助（NIH和 国防部）。 已投入大量精力征聘 更多的少数民族学生加入该计划。 广告已经投放 发表在《科学》杂志和美国癌症研究协会上 会议和内分泌学会会议。 基于我们的期望， 将保持相同的候选人库的高素质的申请人，我们 要求每年继续资助四个博士后职位， 在本申请中为五年。 这将使我们能够 继续专注于信号转导和癌症的博士后培训。

DESCRIPTION (provided by applicant): This application is a request for continued funding of T32 CA70085 at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. The Cancer Center is funded by a support grant from the NCI (P30 CA60553). In addition, the Cancer Center has received two SPORE grants [SPORE in Breast Cancer (P50 CA89018) and SPORE in Prostate Cancer (P50 CA90386)] from the NCI. The Training Program in Signal Transduction and Cancer brings together principal investigators and postdoctoral fellows with a focused interest in hormones, receptors, growth factors and signal transduction pathways. This has been accomplished through organized meetings, journal clubs and seminars and symposia. These activities provide enhanced opportunities for sharing the latest scientific results and promote increased interactions. The preceptors are all established NIH funded investigators and they belong to all four basic science programs of the Cancer Center: Viral Oncogenesis; Tumor Invasion, Metastasis and Angiogenesis; Signal Transduction and Cancer; and Cancer Genes and Molecular Regulation. The Program has successfully trained 13 postdoctoral fellows, including two minority trainees, during the last five years. Trainees attend the educational activities (laboratory meetings, journal club, seminars, symposia) associated with the Program in addition to their laboratory research. Five trainees successfully competed for extramural national funding (NIH and Department of Defense). Significant effort has been invested to recruit additional minority students to the Program. Advertisements have been placed in the journal Science and at the American Association for Cancer Research Meeting and the Endocrine Society Meeting. Based on our expectation that we will maintain the same candidate pool of highly qualified applicants we request continued funding for the four postdoctoral positions per year for a period of five years in the present application. This will enable us to continue focused postdoctoral training in Signal Transduction and Cancer.