HOMEOBOX GENES AND THEIR TARGETS IN XENOPUS DEVELOPMENT

非洲爪蟾发育中的同源盒基因及其靶点

• 批准号: 7016372
• 负责人: EDWARD M DE ROBERTIS
• 金额: $ 32.66万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-04-01 至 2007-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7016372
• 关键词: Xenopus; alternatives to animals in research; body regions; cell differentiation; developmental genetics; ectoderm; embryogenesis; endoderm; gene expression; gene induction /repression; genetically modified animals; homeobox genes; immunoprecipitation; in situ hybridization; mesoderm; messenger RNA; microinjections; molecular cloning; nucleic acid sequence; regulatory gene; transfection; vertebrate embryology

项目成果

Darmin is a novel secreted protein expressed during endoderm development in Xenopus.

Darmin 是非洲爪蟾内胚层发育过程中表达的一种新型分泌蛋白。

• DOI: 10.1016/s1567-133x(03)00011-5
• 发表时间: 2003
• 期刊: Gene expression patterns : GEP
• 作者: Pera,EdgarM;Martinez,SarahL;Flanagan,JohnJ;Brechner,Mariel;Wessely,Oliver;DeRobertis,EM
• 通讯作者: DeRobertis,EM

Endodermal Nodal-related signals and mesoderm induction in Xenopus.

非洲爪蟾内胚层节点相关信号和中胚层诱导。

• DOI: 10.1242/dev.127.6.1173
• 发表时间: 2000
• 期刊: Development (Cambridge, England)
• 作者: Agius,E;Oelgeschläger,M;Wessely,O;Kemp,C;DeRobertis,EM
• 通讯作者: DeRobertis,EM

Deletion mutants of BMP folding variants act as BMP antagonists and are efficient inhibitors for heterotopic ossification.

BMP 折叠变体的缺失突变体可作为 BMP 拮抗剂，是异位骨化的有效抑制剂。

• DOI: 10.1359/jbmr.2003.18.12.2142
• 发表时间: 2003
• 期刊: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
• 作者: Weber,FranzE;Schmokel,Hugo;Oelgeschlager,Michael;Nickel,Joachim;Maly,FriedrichE;Hortschansky,Peter;Gratz,KlausW
• 通讯作者: Gratz,KlausW

[The head inducer Cerberus in a multivalent extracellular inhibitor].

[多价细胞外抑制剂中的头部诱导剂 Cerberus]。

• 发表时间: 1999
• 期刊: Journal de la Societe de biologie
• 作者: Agius,PE;Piccolo,S;DeRobertis,EM
• 通讯作者: DeRobertis,EM

Molecular mechanisms of cell-cell signaling by the Spemann-Mangold organizer.

Spemann-Mangold 组织器的细胞间信号传导的分子机制。

• 发表时间: 2001
• 期刊: The International journal of developmental biology
• 作者: DeRobertis,EM;Wessely,O;Oelgeschläger,M;Brizuela,B;Pera,E;Larraín,J;Abreu,J;Bachiller,D
• 通讯作者: Bachiller,D