Developing Treatment for Older Adolescents with ADHD

为患有多动症的老年青少年开发治疗方法

• 批准号: 7211653
• 负责人: Steven W. Evans
• 金额: $ 19.68万
• 依托单位: JAMES MADISON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7211653
• 关键词: adolescence (12-20); attention deficit disorder; behavioral /social science research tag; clinical research; handbook; health education; hospital community relations; human subject; human therapy evaluation; patient oriented research; psychotherapy; social behavior disorders; social psychology; therapy compliance; therapy design /development; training

DESCRIPTION (provided by applicant): This application is for a "From Intervention Development to Services: Exploratory Research Grants (R34)" in response to PAR-03-078. The proposal is a Stage I development project to develop and conduct a preliminary evaluation of a set of psychosocial interventions for high school aged adolescents with ADHD. The rationale for this project follows from evidence documenting the presence of significant impairment in this population, a decline in the use of medication treatment during these years, and a lack of any reported psychosocial interventions. A treatment manual, training materials, fidelity procedures, assessment instruments, and related materials will be prepared using input from a community development team and experience gained providing these treatment services. Results from pilot studies will provide estimates of effect sizes to inform the planning of future studies, provide data on feasibility and acceptability, and generate hypotheses about moderators and mediators of treatment. The procedures include both clinician and paraprofessional delivered services targeting social impairment and academic problems in the school, community, and family contexts. Some of the interventions are modifications of techniques that have been developed and evaluated for middle school aged adolescents with ADHD. Paraprofessional coaches provide a large portion of the services focusing primarily on the generalization of behaviors to their natural settings. Treatment delivery has been designed to be responsive to the unique developmental issues associated with older adolescents. Like other psychosocial treatments for individuals with chronic disorders, providing medication education to encourage appropriate evaluations and adherence to prescribed medication is an important component of this treatment. During year 01, 10 subjects will be recruited to receive the treatment. The experience and data gained from this will guide the refinement of procedures prior to a pilot clinical trial in years 02 and 03 (n=36). In addition to group differences (treatment vs. community care) analyses will examine rates of attrition, mean number of sessions completed, mean treatment satisfaction ratings, and the proportion of subjects who achieve at least a 0.5 or 1.0 effect size improvement on outcome measures. Exploratory analyses of hypotheses related to potential moderators (gender, comorbid conditions, etc.) and mediators (medication usage, attendance, adherence, etc.) will be completed to inform future work.

描述（由申请人提供）：此申请是针对响应PAR-03-078的“从干预开发到服务：探索性研究补助金（R34）”。该提案是一项I阶段开发项目，旨在开发和进行针对患有多动症的高中青少年的一组心理社会干预措施的初步评估。该项目的基本原理是从证据记录了该人群中存在重大损害的证据，在这些年中使用药物治疗的使用下降以及缺乏任何报告的社会心理干预措施。将使用社区开发团队的意见来准备一项治疗手册，培训材料，保真度程序，评估工具和相关材料，并获得这些治疗服务的经验。试点研究的结果将提供效果大小的估计，以告知未来研究的计划，提供有关可行性和可接受性的数据，并产生有关调节者和治疗介质的假设。这些程序包括针对学校，社区和家庭环境中的社会障碍和学术问题的临床医生和专业专业提供的服务。其中一些干预措施是针对患有多动症的中学年龄的青少年开发和评估的技术的修改。专业教练提供了很大一部分服务，主要关注其自然环境的行为的概括。治疗的旨在响应与老年青少年相关的独特发展问题。像其他针对患有慢性疾病的人的社会心理治疗一样，提供药物教育以鼓励适当的评估和遵守处方药是这种疗法的重要组成部分。在01年期间，将招募10名受试者接受治疗。从此获得的经验和数据将指导在02年和03年（n = 36）进行试验临床试验之前的程序的完善。除了群体差异（治疗与社区护理）外，分析还将检查流失率，平均课程数量，平均治疗满意度等级以及实现至少0.5或1.0效果大小改善结果指标的受试者的比例。将完成与潜在主持人（性别，合并症等）和调解人（药物使用，出勤，依从性等）相关的假设的探索性分析，以告知未来的工作。