Strengthening Bioethics Capacity and Justice in Health

描述（由申请人提供）：在稀缺和不平等的环境中进行人类受试者研究需要上下文敏感的伦理，该伦理包含基本的跨文化价值观并促进社会变革。我们建议通过扩大与北卡罗莱纳大学（UNC）和比利时鲁汶天主教大学（UCL）的伙伴关系，在刚果民主共和国金沙萨公共卫生学院（KSPH）建立生物伦理培训和研究能力。四名刚果学者将在伦敦大学学院完成为期一年的生物伦理学研究生、硕士水平的强化培训项目，并在北卡罗来纳大学完成为期5个月的生物伦理学研究发展、课程建设和IRB培训。在返回刚果民主共和国后，新的KSPH生物伦理中心（CB）的学者将加强当地的IRB能力；进行创新和社会相关的独立生物伦理学研究；将为期两周的生物伦理学模块整合到KSPH的公共卫生硕士项目中；建立生物伦理文件和咨询服务；创作以发展中国家生物伦理问题为重点的原创教材；设计一个生物伦理学网站，开发电子学习能力，并在第四年为来自非洲法语国家的学者提供为期两周的生物伦理学强化课程。新的KSPH生物伦理中心的各种活动将服务于其在刚果民主共和国和非洲法语国家促进负责任的生物医学研究和临床实践的使命。CB将鼓励在贫穷和不公正的情况下反思自治的意义；社区、研究机构和弱势主体之间的共同责任；创造性地、在文化上引起共鸣地解决生物医学研究引起的伦理冲突；认识到程序性知情同意的重要性和局限性，以及体现研究者和受试者之间相互尊重的“协商同意”的必要性。公民责任对于负责任地处理植根于地方和全球不公正的公共卫生问题至关重要，并可促进社会变革和建立新的人权文化。

DESCRIPTION (provided by applicant): Human subjects research in environments of scarcity and inequality requires context-sensitive ethics that incorporates basic transcultural values and promotes social change. We propose to build bioethical training and research capacity at the Kinshasa School of Public Health (KSPH), Democratic Republic of Congo (DRC) through expansion of its partnerships with the University of North Carolina (UNC), and the Catholic University of Louvain, Belgium (UCL). Four Congolese scholars will complete a one-year intensive postgraduate, master-level training program in Bioethics at UCL, and 5 months of mentored bioethics research development, curriculum building, and IRB training at UNC. Upon return to DRC, scholars at the new KSPH Center of Bioethics (CB), will reinforce local IRB capacity; perform innovative and socially relevant independent bioethics research; develop a two-week bioethics module integrated into the MPH program at KSPH; establish a bioethics documentation and consultation service; create original pedagogical material focusing on developing world bioethical issues; design a bioethics website and develop e-learning capacities, and in the fourth year, offer a 2-week intensive course in bioethics for scholars from throughout Francophone Africa. The diverse activities at the new KSPH Center of Bioethics will serve its mission to promote responsible biomedical research and clinical practice in DRC and in francophone Africa. The CB will encourage reflection on the meaning of autonomy in circumstances of poverty and injustice; co-responsibility between communities, research institutions and vulnerable subjects; creative, culturally resonant solutions to ethical conflicts raised by biomedical research; recognition of the importance and limits of procedural informed consent, and the need for 'negotiated consent' embodying mutual respect between researcher and subject. The CB is critical to deal responsibly with public health problems rooted in local and global injustice, and can contribute to social change and the establishment of a new human rights culture.