PROJ 2:UCC:HCV RISK REDUCTION INTERVENTION AS SECONDARY CO-MORBIDITY PREVNT

描述（由申请人提供）： 该提案将为艾滋病毒/艾滋病领域健康差异研究综合中心建立业务和研究基础设施。这是独特而重要的，因为这是第一次在PR三个认可的医学院（UPR医学院，UCC医学院和Ponce医学院）将合作伙伴在一个共同的追求。该中心的一些具体目标是：（1）通过这三所学校之间的合作加强临床和转化研究，（2）为未来建立这种传统或“合作文化”，（3）制定针对波多黎各人口的可持续，可复制和文化上适当的预防和/或干预研究计划，以减少疾病负担，（4）开发和验证一系列文化上适当的工具，以衡量各种变量，例如但不限于：社会人口、艾滋病毒风险行为、合并症、坚持、耻辱、暴力和虐待史;并将其提供给感兴趣的研究人员和医疗保健提供者，（6）利用本地及海外资源，为初级调查人员设立导师计划（公共关系和美国机构），并创造刺激的学术环境，鼓励学生和研究员追求健康差异研究的职业生涯，特别是，艾滋病毒/艾滋病研究和（7）增加岛屿机构与美国大陆更成熟的研究计划之间的多学科研究合作的机会。在第一阶段，将建立中心的业务基础设施，并为每个机构的一个试点项目提供支持。在第二阶段，这些试点项目将成为研究项目，新的年轻研究人员将通过试点项目加入中心。教师发展的一个强大的核心组成部分将确保该中心的调查人员的增长和生产力。其他核心活动将成为数据 中心，实验室，CRC，出版物办公室在作家/编辑的协助下，并招募了3名健康差异调查员。

DESCRIPTION (provided by applicant): This proposal will establish the operational and research infrastructure for a Comprehensive Center for the study of Health Disparities in the area of HIVIAIDS. It is unique and important because for the first time the three accredited Medical Schools in PR (UPR School of Medicine, UCC School of Medicine, and Ponce School of Medicine) will collaborate as partners in a common pursuit. Some of the specific aims of the center are: (1) the enhancing of clinical and translational research through collaboration among these three schools, (2) to establish this tradition or "culture of collaboration" for the future, (3) to develop sustainable, replicable and culturally appropriate prevention and/or intervention research programs targeted to the Puerto Rican population to decrease the burden of disease, (4) to develop and validate a series of culturally appropriate instruments to measure diverse variables such as but not limited to: sociodemographic, HIV risk behaviors, co-morbidities, adherence, stigma, history of violence and abuse; and to make them available to interested investigators and health care providers, (6) to establish a Mentorship program for junior investigators with resources from both local and abroad (PR and US institutions) and to create the stimulating academic environment that will encourage students and fellows to pursue a career in health disparities research and in particular, HIV/AIDS research and (7) to enhance the opportunities for multidisciplinary research collaborations between the island institutions and those with a more established research programs in the US mainland. During a Phase I the operational infrastructure of the center will be established and one pilot project per institution will be supported. During the Phase II, these pilot projects will become research projects and new young investigators will join the Center through pilot projects. A strong Core component of faculty development will assure the growth and productivity of the center's investigators. Other Core activities will be a Data Center, a Lab, a CRC, a publications office with the assistance of a writer/editor, and the recruitment of 3 health disparities investigators.