Formulation of a pan-species, multi-stage vaccine for the malaria eradication agenda

GNTT 1093311题为“为根除疟疾议程制定一种泛物种、多阶段疫苗”，旨在开展针对所有主要疟疾物种和阶段的糖结合疫苗的临床前开发。目标是：(I)进行疫苗结构的合成；(Ii)比较各种疫苗结构的免疫原性、配方和效力，以期下选择最佳组合用于人体临床试验。

GNT 1093311 entitled 'Formulation of a pan-species, multi-stage vaccine for the malaria eradication agenda' seeks to undertake the preclinical development of a saccharide conjugate vaccine directed towards all major species and stages of malaria. The objectives are: (i) to undertake the synthesis of the vaccine construct; (ii) to compare immunogenicity, formulation and efficacy of various vaccine constructs with a view to down-selecting the optimal combination to take to human clinical trial.