Biodiversity of Vietnam and Laos

越南和老挝的生物多样性

• 批准号: 7077702
• 负责人: DJAJA D SOEJARTO
• 金额: $ 83万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7077702
• 关键词: angiosperms; antiAIDS agent; antimalarial agents; antineoplastics; antitubercular agents; biomedical facility; chemoprevention; clinical research; cooperative study; culture; drug discovery /isolation; field study; folk medicine; geographic site; handbook; human subject; information systems; international cooperation; medicinal plants; plant ecology; sample collection; science education; southeast Asia; systematic biology

DESCRIPTION (provided by applicant): This proposed Phase II UIC ICBG (University of Illinois at Chicago-based ICBG) is a continuation of Phase I UIC ICBG, which has been in operation since October 1, 1998, until September 30, 2003. The specific aims of this proposed Phase II mirror those for Phase I, but with long-term second level achievements as follows: (i) integrated effort of biodiversity inventory and conservation at Cuc Phuong National Park (CPNP) in Vietnam, that will include the preparation of a Manual for taxonomic identification of the flowering plants in the park, the establishment of a Threatened Plants Rescue Center, the implementation of a conservation education program, and the transfer of GIS-based biodiversity assessment technology to Vietnam; (ii) integrated study of medicinal plants of Laos through the strengthening of the Lao Medicinal Plant Database and through a comparative ethnobotany mapping project in selected ecogeographic zones in Laos; (iii) collection of plant samples at CPNP and in Laos as an integral part of the UIC ICBG drug discovery effort during Phase II; (iv) expanded program in Phase II effort in the discovery and development of anti-HIV, anti-malaria, anti-TB, and cancer chemoptherapeutic and chemopreventive agents from plants of Vietnam and Laos; (v) setting up the infrastructure and the human resource for the preservation of traditional knowledge in the uses of plants in primary health care of local communities through the establishment of new and the upgrading of existing ethnomedical gardens established during Phase I; and, lastly, (vi) strengthening the capacity (institutional infrastructure and human resources) of host institutions in Vietnam and Laos, in higher level of expertise, to undertake research in biodiversity study and conservation, ethnobotany, and plant-based drug discovery far into the future, beyond ICBG. These specific aims are to be achieved through the close and synergistic cooperations of four Associate Programs (AP's), each with the following responsibility: (i) biodiversity inventory and conservation at CPNP (AP-1); studies on medicinal plants of Laos (AP-2); (iii) drug discovery from plants of Laos and Vietnam for AIDS, cancer, malaria and tuberculosis therapies (AP-3); and (iv) biomass production and economic development (AP-4). These four AP's will be coordinated by a Group Program, under the direction of the U C ICBG Principal Invest gator. The creation of the 4 AP's is necessary for the achievements of the specific aims as stated.

描述(由申请人提供)：建议的第二阶段UIC ICBG(位于芝加哥的伊利诺伊大学ICBG)是第一阶段的延续，第一阶段自1998年10月1日开始运行，至2003年9月30日。这一拟议的第二阶段的具体目标与第一阶段的目标相同，但具有长期的第二级成就，具体如下：(I)在越南的Cuc Phuong国家公园(CPNP)开展生物多样性清查和养护的综合工作，其中将包括编写一份关于公园内开花植物的分类鉴定手册，建立一个濒危植物救助中心，实施一项保护教育方案，并向越南转让基于地理信息系统的生物多样性评估技术；(Ii)通过加强老挝药用植物数据库和老挝选定的生态地理区域的比较民族植物学绘图项目，对老挝的药用植物进行综合研究；(3)在CPNP和老挝收集植物样本，作为UIC ICBG第二阶段药物发现工作的组成部分；(4)在第二阶段扩大方案，从越南和老挝的植物中发现和开发抗艾滋病毒、抗疟疾、抗结核病和癌症化学治疗和化学预防药物；(5)建立基础设施和人力资源，通过建立新的和更新第一阶段建立的现有民族医药花园，在当地社区的初级保健中利用植物进行传统知识的保存；最后，(Vi)加强越南和老挝主办机构的能力(体制基础设施和人力资源)，使其具备更高水平的专业知识，在生物多样性研究和保护、民族植物学和远在未来的植物药物发现方面开展研究，而不仅仅是国际生物多样性公约。这些具体目标将通过四个伙伴项目(AP‘s)的密切和协同合作来实现，每个AP项目的职责如下：(I)CPNP生物多样性清单和保护(AP-1)；(Ii)老挝药用植物研究(AP-2)；(Iii)从老挝和越南植物中发现治疗艾滋病、癌症、疟疾和结核病的药物(AP-3)；以及(Iv)生物质生产和经济发展(AP-4)。这四个AP将在加州大学ICBG首席投资人的指导下，由一个集团项目进行协调。创建4个行动计划对于实现上述具体目标是必要的。