BOUN HOONG SOUTHAVONG LAO MEDICINAL PLANTS--POTENTIAL SOURCE OF NEW MEDICINES

BOUN HOONG SOUTHAVONG 老挝药用植物——新药的潜在来源

• 批准号: 6663462
• 负责人: DJAJA D SOEJARTO
• 金额: $ 13.47万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2003-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6663462
• 关键词: antimalarial agents; antiviral agents; bioassay; central nervous system disorders; community; computer system design /evaluation; cooperative study; data collection; ethnic group; folk medicine; health care; health education; human subject; information retrieval; information systems; international cooperation; interview; medicinal plants; plant extracts; southeast Asia

Associate Program 2 will be performed by the Research Institute of Medicinal Plants (RIMP), Vientiane, Laos. RIMP maintains a network of Traditional Medicine stations in different areas of Laos, through which it will conduct field interviews among the different ethnic groups in Laos regarding use of medicinal plants. Those with uses for Malaria, viral diseases and CNS-related symptoms will be emphasized. Plants with these uses will be collected in bulk samples and extracted at the Phytochemistry Laboratory in RIMP; those with uses against viral disease and malaria will be sent to AP-3 (Program for Collaborative Research in the Pharmaceutical Sciences, University of Illinois at Chicago), while those with uses against CNS-related symptoms will be sent to AP-5 (Glaxo Wellcome Research and Development). Voucher herbarium specimens of all medicinal plants will be collected as far as possible, and systematic data taken on their collection and use. Plant species identifications and medicinal uses of plants will be entered into the NAPIS data management system to assemble a database of plant uses which will act as a basis for further study of the medicinal plants of Laos. Identified species will be analyzed using printouts from the NAPRALERT database and other literature to evaluate potential toxicity and efficacy. Results of this analysis will be communicated to the scientific community through publications. Conservation status of Laos medicinal plants will be examined so that appropriate recommendations for protection of various species may be made to the Lao PDR Government. Community health promotion and promotion of children's education will be the major efforts of reciprocity for communities that collaborate with RIMP investigators; support of the network of Traditional Medicine Stations will also be part of reciprocity, as these Stations assist RIMP in maintaining contact with ethnic communities, as well as serving the health needs of those communities. Finally, human resources and infrastructure upgrading at RIMP will take place, including international training in ethnobotanical research, phytochemistry, and conservation biology.

副项目2将由研究所执行， 药用植物（RIMP），万象，老挝. RIMP维护着一个网络， 在老挝不同地区的传统医药站，通过它， 将在老挝的不同民族中进行实地采访 关于药用植物的使用。用于治疗疟疾的病毒 疾病和中枢神经系统相关症状将得到强调。植物与这些 将在植物化学实验室收集大量样品并提取 RIMP实验室;那些用于治疗病毒性疾病和疟疾的实验室将 AP-3（制药领域合作研究计划） 科学，伊利诺伊大学芝加哥分校），而那些使用 针对CNS相关症状的研究将被发送到AP-5（Glaxo Wellcome Research 和发展）。所有药用植物的植物标本馆标本将 尽可能地收集，并系统地收集他们的数据。 收集和使用。植物种类鉴定及药用 工厂将进入NAPIS数据管理系统， 一个植物用途数据库，作为进一步研究的基础， 老挝的药用植物将使用以下方法分析已识别的种属 NAPRALERT数据库和其他文献中的主要内容，以评估 潜在的毒性和功效。分析结果将是 通过出版物传播给科学界。 将对老挝药用植物的保护状况进行检查， 可以提出保护各种物种的适当建议 老挝人民民主共和国政府社区健康促进和促进 孩子的教育将是互惠的主要努力， 与RIMP调查人员合作的社区; 传统医药站网络也将是互惠的一部分， 因为这些电台协助RIMP与少数民族保持联系， 社区，并满足这些社区的健康需求。 最后，RIMP的人力资源和基础设施升级将 地方，包括民族植物学研究的国际培训， 植物化学和保护生物学。