BIOMOLECULE CHARACTERIZATION AND SEPARATION CORE FACILITY

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。得克萨斯大学埃尔帕索分校提议继续支持一个专门从事生物分子分离和表征的多用户研究设施，即分子生物学核心设施。该设施维护的设备包括离心机、超浓缩器、伽马和闪烁计数器、配有许多检测器的高效液相色谱仪、毛细管电泳、紫外/维斯光光度计、微孔板阅读器和许多其他共用设备。许多其他资源也可用于记录和分析使用这些仪器收集的实验数据。目前，该核心还配备了核酸的合成和扩增。由于可能的迁移和与受影响的用户群体的讨论，这些能力可能会重新组织，以更好地满足用户的需要。该设施的目的是为尽可能广泛的用户群体提供维护良好的最先进设备。每个房间都有两个房间，每个房间都有超过1000次，每月有100多名个人用户进入，代表15个以上的研究小组。该设施将配备一名全职协调员，负责日常维护、工厂代表安排预防性维护、用户指导和协助以及账户和库存维护。将向核心主任提供部分薪金，以持续监督这些活动

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Texas at El Paso proposes continuing support for a multi-user research facility specializing in the separation and characterization of biomolecules, the molecular biology core facility. This facility maintains equipment such as centrifuges, ultracentrifuges, gamma and scintillation counters, HPLC with numerous detectors, capillary electrophoresis, UV/vis spectrophotometers, microplate readers and many other items of shared equipment. Numerous other resources are available as well to document and analyze experimental data collected using these instruments. Currently, this core is also equipped for the synthesis and amplification of nucleic acids. These capabilities may be reorganized to better serve the needs of users as a result of possible relocation and discussions with affected user groups. The purpose of this facility is to provide the broadest possible group of users with access to well maintained, state of the art, equipment. Each of two rooms housing these instruments is entered more than 1000 times per month by more than 100 individual users, representing more than 15 research groups. This facility will be staffed by a full-time coordinator who will be responsible for routine maintenance, scheduling preventative maintenance by factory representatives, user orientation and assistance as well as account and inventory maintenance. Partial salary will be provided to the core director for ongoing oversight of these activities