Parent Intervention in CBT for Depressed Latino Youth

家长对抑郁拉丁裔青少年进行 CBT 干预

• 批准号: 7245711
• 负责人: GUILLERMO BERNAL
• 金额: $ 10.85万
• 依托单位: UNIVERSITY OF PUERTO RICO RIO PIEDRAS
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7245711
• 关键词: Hispanic Americans; Puerto Rican; adolescence (12-20); behavioral /social science research tag; clinical research; clinical trials; cognitive behavior therapy; family structure /dynamics; functional ability; health disparity; human subject; human therapy evaluation; interview; longitudinal human study; major depression; mental disorder diagnosis; mental disorder prevention; mental health education; outcomes research; parent offspring interaction; patient oriented research; relapse /recurrence

DESCRIPTION (provided by applicant): Despite progress in treating mental disorders in youth, little is known about these interventions with Latinos who are now the largest minority group in the United States. This study examines the impact of enhancing effective interventions through the involvement of parents in an 8 session of a psycho education intervention (PPI). This PPI will be incorporated into the 12-session CBT, a Cognitive Behavioral treatment method that has already been shown effective for the treatment of adolescent depression. This study will randomize 140 Latino adolescents with Major Depression to CBT with or without a PPI delivered in groups. Intake diagnoses will be obtained via structured diagnostic interviews (Diagnostic Interview Schedule for Children-DISC for adolescents and Composite International Diagnostic Interview-CIDI for parents). The study will focus on Puerto Rican adolescents and their parents. The primary aims address both the efficacy and effectiveness of the intervention and treatments. Efficacy questions focus on the comparison of the active treatment with and without the PPI for reducing depressive symptoms and diagnosis (DISC) after 12 weeks of treatment and for preventing relapse over the course of one year post-treatment (DISC). Effectiveness questions focus on the impact of the treatment with or without the PPI on broader functional outcomes. Patient functional outcomes include general functioning status, family functioning, school attendance, and attrition rates. The relative value of CBT with and without the adjunctive parent intervention for improved parent functioning regarding psychiatric distress and symptoms, burden of patient illness, and work attendance will be examined. We hypothesize that the active treatment with PPI will be superior to no PPI in reducing depression at post treatment. Because the PPI is designed to involve parents and thus impact other aspects of the family system, this treatment is expected to produce better outcomes in several of the functional domains. To test the theoretical assumptions of the intervention, we also aim to examine the contribution of hypothesized treatment-specific change mechanisms to mediate the short-term outcome and predict long-term relapse over one year. This study responds to NIH and NIMH initiatives on decreasing disparities in health and mental health care between minorities and White populations and will contribute to our knowledge base.

描述（由申请人提供）：尽管在治疗青年的精神障碍方面取得了进展，但对于现在是美国最大的少数群体的拉丁裔的干预措施知之甚少。这项研究研究了通过父母参与精神教育干预措施（PPI）的8次会议来增强有效干预措施的影响。该PPI将被纳入12阶段CBT，这是一种认知行为治疗方法，已经显示出有效治疗青少年抑郁症。这项研究将对有或没有PPI组的CBT随机将140名具有严重抑郁症的拉丁裔青少年随机。摄入诊断将通过结构化的诊断访谈（青少年儿童-DISC的诊断访谈时间表和父母的综合国际诊断访谈-CIDI）获得。该研究将重点关注波多黎各人的青少年及其父母。主要目的既解决干预和治疗的功效和有效性。功效问题的重点是与有或没有PPI的主动治疗进行比较，以减少治疗12周后减少抑郁症状和诊断（DISC），并防止治疗后一年（DISC）进行一年的复发。有效性问题的重点是有或没有PPI对更广泛功能结果的治疗的影响。患者功能结果包括一般功能状态，家庭功能，出勤率和流失率。将检查有或没有辅助父母干预的CBT的相对价值，以改善父母在精神病困扰和症状，患者疾病的负担以及出勤率上的工作。我们假设使用PPI的主动治疗在减少治疗后抑郁症方面将优于无PPI。由于PPI旨在使父母参与其中，从而影响家庭系统的其他方面，因此预计这种治疗方法将在几个功能领域产生更好的结果。为了测试干预措施的理论假设，我们还旨在研究假设的治疗特异性变化机制的贡献，以介导短期结局并预测一年内的长期复发。这项研究对NIH和NIMH倡议做出了回应，涉及少数民族和白人人群之间健康和精神保健差异的差异，并将为我们的知识基础做出贡献。