Saving Cassava : A novel gene in a deadly virus

拯救木薯：致命病毒中的新基因

• 批准号: 2746352
• 金额: --
• 依托单位: University of Bristol
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2746352
• 关键词: Saving; Cassava; novel; gene; deadly

Cassava brown streak disease (CBSD), caused by the Cassava brown streak viruses (CBSV) causes losses up to 100% and typically >60-70% of root harvest in susceptible varieties, as well as substantial losses through reducing the market value due to necrotic lesions. CBSD has become an extremely serious constraint to cassava production in East Africa as well as a threat to cassava production throughout Africa. CBSD is listed as one of the seven most dangerous plant diseases in the world for the impact it can have on food and economic security throughout Africa. The aim of this PhD will be to carry out a detailed molecular analysis of a highly unusual gene found within the CBSV that is highly unique to these types of viruses. This PhD will join an international collaborative team working on vector-borne plant diseases in particular plant viruses and will be based in the School of Biological Sciences in the laboratory of Professor Gary Foster and Dr Andy Bailey and working in close collaboration with academics at University of Greenwich, and research groups across Africa.

由木薯褐条病毒（CBSV）引起的木薯褐条病（CBSD）在易感品种中导致高达100%且通常>60-70%的根收获的损失，以及由于坏死病变导致的市场价值降低而造成的实质性损失。CBSD已成为东非木薯生产的一个极其严重的制约因素，并对整个非洲的木薯生产构成威胁。CBSD被列为世界上七种最危险的植物疾病之一，因为它可能对整个非洲的粮食和经济安全产生影响。这个博士学位的目的是对CBSV中发现的一种非常不寻常的基因进行详细的分子分析，这种基因对这些类型的病毒来说是非常独特的。该博士将加入一个国际合作团队，致力于研究媒介传播的植物疾病，特别是植物病毒，并将在生物科学学院加里福斯特教授和安迪贝利博士的实验室工作，并与格林威治大学的学者和非洲各地的研究小组密切合作。