BEAUMONT/DETROIT CONTINENCE TREATMENT CENTER

该项目的主要目标之一是确定最常用的尿失禁手术的长期效果和结果，包括并发症。广泛的文献回顾显示，在本CTC中提出的所有三种外科技术中，成功率(可控性)和改善率似乎相似。虽然两者的并发症可能更独特，但发病率似乎也是相似的。因此，我们不相信可以通过功率计算来估计每个小组需要登记的科目总数。因此，我们认为，受试者的总数可能必须由网络任意决定，以确保有足够数量的患者被观察，以收集所有必要的信息，以满足本研究的目标。大小便失禁治疗的主要目的是改善患者的生活质量。患者对长期随访的满意度在文献中还没有得到充分的报道。这项研究可以为这些问题提供广泛的回顾。然而，进行比较的标准必须由集体调查员商定。此外，拟议手术的经济性也将对整体的医疗经济学结果产生影响。由于报道的治疗成功率之间的相似性，长期成本效益和最终患者满意度的差异可能比仅仅改善大小便失禁症状更能预测总体治疗成功。

One of the major goals of this project is to determine the long term effects and outcomes including complications of the' most commonly used surgical procedures for urinary incontinence. Extensive review of the literature shows that the success rate (continence) and improvement rate appear to be similar among all of the three surgical techniques proposed in this CTC. Although the complications may be more unique with one or the other, it also appears that the morbidity rate is similar. Therefore, we do not believe that a power calculation can be performed to estimate the total number of subjects needed to be enrolled in each group. Therefore, we believe that the total number of subjects may have to be arbitrarily decided by the network to assure an adequate number of patients to be observed to gather all the necessary information to satisfy the objectives of this study. The principal goal of incontinence therapy is to improve the quality of life for the patient. Patient satisfaction in long-term follow-up has not been adequately reported in the literature. This study can provide the extensive review of these issues. However, the criteria on which the comparisons are made will necessarily be agreed upon by the collective investigators. In addition, the economics of the proposed procedures will also have a bearing on the overall medicoeconomic outcomes. Due to the similarities between the reported treatment success rates, differences in long term cost effectiveness and ultimate patient satisfaction may be a better predictor of overall treatment success than improvement of incontinence symptoms alone.