First Congress of Urologic Research and Education on Aging UnderActive Bladder

描述(申请人提供)：膀胱收缩能力和排尿效率随年龄增长而减弱。尿失禁和其他下尿路症状对老年人的健康和独立性有重大影响(Taylor和Kuchel，2006年)。虽然尿失禁通常被认为是由于括约肌虚弱或受损而无法容纳尿液，但它也包括尿液滞留或无法完全排空膀胱，导致滞留和溢出。这也被称为膀胱活动不足或UAB。目前，没有任何药物或疗法被证明对UAB的长期治疗有效，也没有已知的治愈方法。因此，患有UAB的患者使用室内导尿管、清洁的间歇性导尿或必须穿尿布进行管理。这些设备的使用给单独的老年人及其照顾者带来了巨大的困难和挑战。使用导尿管确保膀胱排空的UAB患者也面临长期的医疗困难，包括炎症和不适，有可能受伤，以及细菌感染的风险增加。尿路感染会导致肾脏损伤和血液感染。此外，对许多人来说，使用导尿管是令人尴尬的原因，并可能对他们的工作和家庭生活产生负面影响。事实上，对于许多膀胱活动不足的患者来说，这种疾病的情感影响可能会像身体影响一样具有破坏性。对于年长的患者，它可能会对生活质量产生重大影响。事实上，膀胱控制的LSS是老年人安置养老院的第二大常见原因。找到一种方法来阻止这些膀胱问题，将使数百万老年人保持独立，体验没有与膀胱控制功能障碍相关的担忧和尴尬的生活。大多数专家和公众都没有意识到这一重要问题。首届老年膀胱活动不足泌尿学研究和教育大会(CURE-UAB)旨在解决这一问题，将于2014年2月20日和21日在华盛顿特区大都市区举行，目标是75-100人参加。我们很高兴能组织和参加这一史无前例的活动，这将标志着世界上第一次联合广播公司研讨会。作为第一次也是唯一一次计划专门讨论膀胱活动不足的会议，这次会议将提高人们对老化的UAB的认识。这次会议是在老年医学、泌尿外科、妇科和护理等医学学科领域专家达成共识的基础上计划的。此外，我们已经得到博蒙特、美国泌尿外科疾病基金会(AFUD)、泌尿外科护士学会(SUNA)、老年泌尿外科学会(GUS)和不活跃膀胱基金会的支持和投入。影响：UAB是一个不断扩大的令人头疼的老龄化健康问题，对老年人的健康和独立性产生了重大影响，但受到的关注程度极低。CURE-UAB将组织有史以来第一次关键利益攸关方关于这一主题的国际会议。我们博蒙特的团队拥有一支经验丰富的研究团队和专家合作者，拥有成功完成这一项目的独特才华。在美国国立卫生研究院的支持下，CURE-UAB将成功地教育公众、学术界、产业界和政府的利益相关者，从而改善数百万美国人的医疗保健。

DESCRIPTION (provided by applicant): Bladder contractility and voiding efficiency diminish with age. Urinary incontinence and other lower urinary tract symptoms exert a major influence on the health and independence of older people (Taylor and Kuchel 2006). Although urinary incontinence is often thought of as the inability to hold in urine because of a weak or damaged sphincter, it also includes issues of urinary retention or the inability to completely empty the bladder, leading to retention and overflow. This is also known as underactive bladder or UAB. Currently, no medications or therapies have proven effective in the long-term treatment of UAB and no known cure exists. As a result, patients who suffer from UAB are managed with in-dwelling catheters, clean intermittent catheterization, or must wear diapers. Use of these devices creates immense difficulties and challenges for elderly individually and their caretakers. UAB patients using catheters to ensure the emptying of their bladders also face long-term medical difficulties, including inflammation and discomfort, the potential for injury, and an increased risk of bacterial infection. Urinary tract infections can lead to kidney damage and blood infections. In addition, for many individuals, the use of catheters is a cause for embarrassment and can negatively impact their work and home life. Indeed, for many patients with underactive bladder, the emotional effects of the disease can feel just as devastating as the physical effects. And for older patients, it can have a major impact on quality of life. In fact, lss of bladder control is the second most common reason for nursing home placement of the elderly. Finding a way to stem these bladder issues would allow millions more older adults to remain independent and experience life without the worry and embarrassment associated with bladder control dysfunction. This important issue is below the radar of most experts and the public. The inaugural First Congress of Urologic Research and Education on Aging UnderActive Bladder (CURE-UAB) seeks to address this issue and will be held on February 20 and 21, 2014 in the Washington, D.C. metropolitan area with target of 75-100 attendees. We are excited to organize and participate in this unprecedented event which will mark the first UAB symposium in the world. As the first and only planned meeting dedicated to the underactive bladder, the conference will create awareness for the aging UAB. This meeting is being planned based on a consensus of experts in the field spanning the medical disciplines of geriatric medicine, urology, gynecology and nursing. Moreover, we have already received the support and input of Beaumont, American Foundation of Urological Disease (AFUD), Society of Urological Nurses (SUNA), Geriatric Urological Society (GUS), and the Underactive Bladder Foundation. Impact: UAB is an expanding troublesome health issue of aging, exerting a major influence on the health and independence of older people with a disproportionally low level of attention received. CURE-UAB will organize the first ever international gathering of key stakeholders on this topic. Our team at Beaumont, with an experienced research team and expert collaborators, has the unique talent to successfully complete this project. With the support of the NIH, CURE-UAB will successfully educate the public, academic, industry and governmental stakeholders that can lead to the improved the healthcare for millions of Americans.